Results 261 to 270 of about 632,889 (322)

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Biosynthesis of patchoulol via metabolic engineering the oleaginous red yeast <i>Rhodotorula toruloides</i>. [PDF]

Synth Syst Biotechnol
Zheng X, Li Y, Liu Z, Sun P, Dong Y, Wang X, Wang Y, Yang X.   +7 more
europepmc   +1 more source

Chemoselective Sequential Polymerization: An Approach Toward Mixed Plastic Waste Recycling

Advanced Functional Materials, EarlyView.
Inspired by biological protein metabolism, this study demonstrates the closed‐loop recycling of mixed synthetic polymers via ring‐closing depolymerization followed by a chemoselective sequential polymerizations process. The approach recovers pure polymers from mixed feedstocks, even in multilayer formats, highlighting a promising strategy to overcome a
Gadi Slor, Youwei Ma, Hyunwoo Park, Tae‐Lim Choi, Damien Guironnet, Francesco Stellacci   +5 more
wiley   +1 more source

Systematic metabolic engineering of <i>Escherichia coli</i> for high-level production of pseudouridine via pathway optimization and precursor enhancement. [PDF]

Synth Syst Biotechnol
Song J, Shen W, Xia Y, Zhou L, Zhou Y, Yang H, Chen X.   +6 more
europepmc   +1 more source

Supplementary file 2_Improving butenyl-spinosyn production in Saccharopolyspora pogona through combination of metabolic engineering and medium optimization.xlsx

Xueli Zhao (212505), Haisong Lu (6447032), Sen Peng (7488035), Haifeng Hang (4431280), Waleed Aldahmash (6559808), Muath Q. Al-Ghadi (17876863), Weihua Tang (1500325), Jiang Pei (21163919), Wan Xun (21163922), Meijin Guo (308550), Ali Mohsin (1895746)   +10 more
openalex   +1 more source

Metabolic engineering of Mannheimia succiniciproducens for enhanced production of succinic acid based on elementary mode analysis with clustering

, 2017
Sang Yup Lee, Hyun Kim, Jung Ho Ahn, Won Jun Kim   +3 more
openalex   +1 more source

Formation of Stable Amorphous Calcium Phosphate and Collagen Assemblies by a Versatile Spray‐Drying Approach

Advanced Functional Materials, EarlyView.
Amorphous calcium phosphate (ACP) microparticles with long‐term and thermal stability are prepared with or without collagen using a scalable one‐pot spray‐drying process. Under simulated physiological conditions, they crystallize into biomimetic bone mineral and, when combined with collagen, form extrudable, fibrillar bone‐like 3D constructs.
Camila Bussola Tovani, Nessma Bennaceur, Celina Benkhellat, Tristan Georges, Clara Doisneau, Vaskar Sardhalia, Thierry Azaïs, Flora Lemaire, Halima Kerdjoudj, Mohamed Selmane, Capucine Sassoye, Marie Albéric, Cédric Boissière, Nadine Nassif   +13 more
wiley   +1 more source

Metabolic engineering of Streptomyces explomaris for increased production of the reverse antibiotic nybomycin. [PDF]

Microb Cell Fact
Shu W, Stegmüller J, Rodriguez-Estevez M, Rückert-Reed C, Kalinowski J, Gromyko O, Rebets Y, Luzhetskyy A, Wittmann C.   +8 more
europepmc   +1 more source

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Metabolic engineering of doxorubicin biosynthesis through P450-redox partner optimization and structural analysis of DoxA. [PDF]

Nat Commun
Koroleva A, Artukka E, Yamada K, Newmister SA, Harte RJ, Boesger H, Londen M, Sanders JN, Tirkkonen H, Kannisto M, Kuin RCM, Hulst M, Wang R, Leskinen E, Barillec M, Niemi J, van Wezel GP, Neefjes J, Nybo SE, Houk KN, Sherman DH, Kim RQ, Metsä-Ketelä M.   +22 more
europepmc   +1 more source