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Metabolic Fluxes and Metabolic Engineering

Metabolic Engineering, 1999
Metabolic engineering is the directed improvement of cellular properties through the modification of specific biochemical reactions or the introduction of new ones, with the use of recombinant DNA technology. As such, metabolic engineering emphasizes metabolic pathway integration and relies on metabolic fluxes as determinants of cell physiology and ...
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Engineering of Secondary Metabolism

Annual Review of Genetics, 2015
Secondary (specialized) metabolites, produced by bacteria, fungi, plants, and other organisms, exhibit enormous structural variation, and consequently display a wide range of biological activities. Secondary metabolism improves and modulates the phenotype of the host producer.
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Cellular and metabolic engineering

Applied Biochemistry and Biotechnology, 1993
Metabolic engineering is defined as the purposeful modification of intermediary metabolism using recombinant DNA techniques. Cellular engineering, a more inclusive term, is defined as the purposeful modification of cell properties using the same techniques. Examples of cellular and metabolic engineering are divided into five categories: 1.
D C, Cameron, I T, Tong
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Metabolic Engineering of Photorespiration

2017
The introduction of two alternative glycolate catabolic pathways in the chloroplasts of Arabidopsis thaliana rendered plants with increased biomass. To introduce these synthetic pathways, the selected genes were stepwise integrated in the nuclear genome of wild-type plants.
Martin K M, Engqvist   +1 more
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Application of Metabolic Flux Analysis in Metabolic Engineering

2011
Metabolic flux analysis (MFA) is an important analytical technique to quantify intracellular metabolic fluxes as a consequence of all catalytic and transcriptional interactions. In systems metabolic engineering, MFA has played important role to understand cellular physiology under particular conditions and predict its metabolic capability after genetic
Lee, SY Lee, Sang-Yup   +2 more
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Systems Metabolic Engineering

2008
Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not ...
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Physiological limitations and opportunities in microbial metabolic engineering

Nature Reviews Microbiology, 2021
JOSÉ Montano Lopez   +2 more
exaly  

Metabolic Engineering: Methodologies and Applications

Chemical Reviews, 2023
Vinh G Tran   +2 more
exaly  

Microalgal metabolic engineering strategies for the production of fuels and chemicals

Bioresource Technology, 2022
Nam Kyu Kang   +2 more
exaly  

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