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Metabolic Fluxes and Metabolic Engineering
Metabolic Engineering, 1999Metabolic engineering is the directed improvement of cellular properties through the modification of specific biochemical reactions or the introduction of new ones, with the use of recombinant DNA technology. As such, metabolic engineering emphasizes metabolic pathway integration and relies on metabolic fluxes as determinants of cell physiology and ...
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Engineering of Secondary Metabolism
Annual Review of Genetics, 2015Secondary (specialized) metabolites, produced by bacteria, fungi, plants, and other organisms, exhibit enormous structural variation, and consequently display a wide range of biological activities. Secondary metabolism improves and modulates the phenotype of the host producer.
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Developments in metabolic engineering
Current Opinion in Biotechnology, 1997The complete sequencing of several microbial genomes has resulted in the increased availability of genes for metabolic engineering. The number of databases and computational tools to deal with this information has also increased. This development has stimulated, and will continue to stimulate, advances in metabolic engineering. Specific recent advances
, Cameron, , Chaplen
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Microbial acetyl-CoA metabolism and metabolic engineering
Metabolic Engineering, 2015Recent concerns over the sustainability of petrochemical-based processes for production of desired chemicals have fueled research into alternative modes of production. Metabolic engineering of microbial cell factories such as Saccharomyces cerevisiae and Escherichia coli offers a sustainable and flexible alternative for the production of various ...
Anastasia, Krivoruchko +4 more
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Metabolic Engineering of Photorespiration
2017The introduction of two alternative glycolate catabolic pathways in the chloroplasts of Arabidopsis thaliana rendered plants with increased biomass. To introduce these synthetic pathways, the selected genes were stepwise integrated in the nuclear genome of wild-type plants.
Martin K M, Engqvist +1 more
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