Results 261 to 270 of about 345,747 (340)

Competitive action network of polyamines metabolic and ethylene biosynthesis pathways in gibberellin-induced parthenocarpic berries during grape fruit setting

Xuxian Xuan, Ziyang Qu, Ehsan Sadeghnezhad, Zhenqiang Xie, Ziyang Qi, Hui Yang, Xiuling Song, Mucheng Yu, Linjia Luo, Rana Badar Aziz, Yanping Zhang, Peijie Gong, Jinggui Fang, Chen Wang   +13 more
openalex   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Metabolomics Network Analysis of Various Genotypes Associated with Schizophrenia Gene Variant. [PDF]

Metabolites
Rajula HSR, Piras C, Kopeć KK, Noto A, Spada M, Lilliu K, Manchia M, Mussap M, Atzori L, Fanos V.   +9 more
europepmc   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

The pathogenic theory of homeostasis threshold deviation (HTD) in wide-range oscillatory physiological parameters: novel perspectives for hypertension and metabolic disease treatment. [PDF]

Life Metab
Sun W, Sun JY, Kong X.
europepmc   +1 more source

Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis

Advanced Healthcare Materials, EarlyView.
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim, Sung Sik Hur, Jae Hong Park, Myung Jin Ban, Jin‐Young Kim, Joo Hyun Kim, Ji Hyae Choo, Hae‐Won Kim, Ju Hun Lee, Man Ryul Lee, Yongsung Hwang   +10 more
wiley   +1 more source

Adipose tissue dysfunction disrupts metabolic homeostasis: mechanisms linking fat dysregulation to disease. [PDF]

Front Endocrinol (Lausanne)
Bou Matar D, Zhra M, Nassar WK, Altemyatt H, Naureen A, Abotouk N, Elahi MA, Aljada A.   +7 more
europepmc   +1 more source

Deciphering Important Metabolic Pathways through Reaction Pair Prediction with a Siamese Transformer Network

Han Bao, Xinxin Wang, Jinhui Zhao, Bin Wang, Xinjie Zhao, Chunxia Zhao, Xin Lu, Guowang Xu   +7 more
openalex   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source

Shared molecular mechanisms between type 2 diabetes and thyroid cancer: integrated bioinformatics insights for prognostic biomarker discovery. [PDF]

Endocr Connect
Qi J, Chen C, Zhu F, Chen C, Wang Y.
europepmc   +1 more source