Ultra‐High‐Throughput Discovery of Multifunctional Polyphenolic Coatings on Droplet Microarrays
An ultra‐high‐throughput (UHT) combinatorial strategy enables the miniaturized synthesis and screening of ≈30 000 polyamine‐polyphenolic (PaPp) coatings using droplet microarrays (DMA). This approach reveals hundreds of previously unknown fluorescent, redox‐active, and antibacterial materials, including multifunctional, cell‐compatible surfaces ...
Vania Tanda Widyaya +11 more
wiley +1 more source
Editorial for the Special Issue "The Role of Bioactives in Inflammation, 2nd Edition". [PDF]
Kuo CY.
europepmc +1 more source
Orienting biochemical reactions in metabolic pathways and networks
This study offers a comprehensive exploration into the orientation of hypergraphs within metabolistic pathways. Our focus was on formulating an AMPL model, enabling researchers to attain effective solutions through ILP optimization. Key contributions of our work encompass: - Development of a logically robust model for solving hyperedge orientation in ...
openaire +1 more source
Oppositely charged single enzyme nanogels (SENs) phase‐separate into bi‐enzymatic coacervate microdroplets, acting as both scaffold and functional units. By tuning SEN ratios, these coacervates create specific microenvironments that enable selective small‐molecule enrichment and efficient intermediate diffusion.
Andoni Rodriguez‐Abetxuko +11 more
wiley +1 more source
Multifaceted mechanisms by which environmental endocrine-disrupting chemicals promote cancer progression: crosstalk among carcinogenesis, immunity, and metabolic reprogramming: narrative mini-review. [PDF]
Du A +7 more
europepmc +1 more source
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang +10 more
wiley +1 more source
Astrocytes and Microglia Regulate Opioid Receptor-Driven Cancer Brain Metastasis and Neural Injury: Remodeling the Brain Microenvironment. [PDF]
Cui D, Wang X, Shang X.
europepmc +1 more source
Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee +3 more
wiley +1 more source
Circular RNAs as diagnostic biomarkers in type 2 diabetes mellitus: implications in metabolic dysfunction and immune-inflammatory crosstalk. [PDF]
Liu Z +6 more
europepmc +1 more source
Parallel wiring of bioelectrochemical devices with conventional generators unexpectedly boosts output. A biophotovoltaic paired with a solar cell delivers up to 50% more power at low loads than their separate contributions; a plant microbial fuel cell shows similar current gains.
Valeria Marsaglia +4 more
wiley +1 more source

