Results 201 to 210 of about 860,607 (312)

Glycolysis: A multifaceted metabolic pathway and signaling hub. [PDF]

J Biol Chem
Kierans SJ, Taylor CT.
europepmc   +1 more source

A Metabolic-Pathway Blockade Approach to Human Longevity: Neutralizing the Effects of Carbohydrate Sugars and Isoleucine Without Dietary Restriction

Izzo, Daniel, Chat, GPT
openalex   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

High-yield zeaxanthin production in Chlamydomonas reinhardtii via advanced metabolic pathway engineering. [PDF]

Biotechnol Biofuels Bioprod
Jang J, Baier T, Kneip JS, Kruse O, Jin E.   +4 more
europepmc   +1 more source

Biotransformation of Cobicistat: Metabolic Pathways and Enzymes

, 2016
Pengcheng Wang, Amina I. Shehu, Ke Liu, Jie Lu, Xiaochao Ma   +4 more
openalex   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Learning motif features and topological structure of molecules for metabolic pathway prediction. [PDF]

J Cheminform
Hu J, Zhang Y, Xie J, Yuan Z, Yin Z, Shi S, Li H, Li S.   +7 more
europepmc   +1 more source

Faculty Opinions recommendation of The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases.

, 2017
Robert Powers, Eli Riekeberg
openalex   +2 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source