Results 61 to 70 of about 4,047,137 (345)
Cancer & Metabolism, 2016 BackgroundColorectal cancers (CRC) are associated with perturbations in cellular amino acids, nucleotides, pentose-phosphate pathway carbohydrates, and glycolytic, gluconeogenic, and tricarboxylic acid intermediates.
Dustin G. Brown +6 more
semanticscholar +1 more source
Targeting the alternative bile acid synthetic pathway for metabolic diseases
Protein & Cell, 2020 The gut microbiota is profoundly involved in glucose and lipid metabolism, in part by regulating bile acid (BA) metabolism and affecting multiple BA-receptor signaling pathways.
Wei Jia +3 more
semanticscholar +1 more source
Research progress in biosynthesis and regulation of plant terpenoids
Biotechnology & Biotechnological Equipment, 2021 Terpenoids are aromatic metabolites in plants. They can improve the adaptability of plants to the environment. Some specialized terpenoids have immense value to people because of the applications to medicine, industry and agriculture.
Ying Huang +3 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
A RuBisCO-mediated carbon metabolic pathway in methanogenic archaea
Nature Communications, 2017 Two enzymes are considered to be unique to the photosynthetic Calvin–Benson cycle: ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO), responsible for CO2 fixation, and phosphoribulokinase (PRK).
Takunari Kono +11 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Optimal Metabolic Pathway Activation [PDF]
IFAC Proceedings Volumes, 2008 14 pages, 3 figures.
Oyarzún, Diego A. +3 more
openaire +4 more sources
Definitions, 2019 An elaboration of the known steps and interactions for the metabolism of a compound.
Ján Labuda +16 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 Non-alcoholic fatty liver disease (NAFLD) is one of the primary causes of cirrhosis and a major risk factor for hepatocellular carcinoma and liver-related death.
Qiang Zhang +23 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source