Results 101 to 110 of about 1,277,321 (205)

Pathway analysis of kidney cancer using proteomics and metabolic profiling

Molecular Cancer, 2006
Background Renal cell carcinoma (RCC) is the sixth leading cause of cancer death and is responsible for 11,000 deaths per year in the US. Approximately one-third of patients present with disease which is already metastatic and for which there is ...
Fiehn Oliver, Lin Pei-Yin, Dhirapong Amy, Valkova Nelly, Lee Jinoo, Perroud Bertrand, Kültz Dietmar, Weiss Robert H   +7 more
doaj   +1 more source

Predicting metabolic pathways of small molecules and enzymes based on interaction information of chemicals and proteins.

PLoS ONE, 2012
Metabolic pathway analysis, one of the most important fields in biochemistry, is pivotal to understanding the maintenance and modulation of the functions of an organism. Good comprehension of metabolic pathways is critical to understanding the mechanisms
Yu-Fei Gao, Lei Chen, Yu-Dong Cai, Kai-Yan Feng, Tao Huang, Yang Jiang   +5 more
doaj   +1 more source

Extreme pathway analysis reveals the organizing rules of metabolic regulation.

PLoS ONE, 2019
Cellular systems shift metabolic states by adjusting gene expression and enzyme activities to adapt to physiological and environmental changes. Biochemical and genetic studies are identifying how metabolic regulation affects the selection of metabolic ...
Yanping Xi, Fei Wang
doaj   +1 more source

Metabolic Dependencies in Pancreatic Cancer. [PDF]

, 2018
Pancreatic ductal adenocarcinoma (PDA) is a highly lethal cancer with a long-term survival rate under 10%. Available cytotoxic chemotherapies have significant side effects, and only marginal therapeutic efficacy. FDA approved drugs currently used against
Brody, Jonathan R., Vaziri-Gohar, Ali, Winter, Jordan M., Zarei, Mahsa   +3 more
core   +1 more source

MACAW: a method for semi-automatic detection of errors in genome-scale metabolic models

Genome Biology
Genome-scale metabolic models (GSMMs) are used to predict metabolic fluxes, with applications ranging from identifying novel drug targets to engineering microbial metabolism.
Devlin C. Moyer, Justin Reimertz, Daniel Segrè, Juan I. Fuxman Bass   +3 more
doaj   +1 more source

Systematic Analysis of Metabolic Pathway Distributions of Bacterial Energy Reserves

G3: Genes, Genomes, Genetics, 2019
Previous bioinformatics studies have linked gain or loss of energy reserves with host-pathogen interactions and bacterial virulence based on a comparatively small number of bacterial genomes or proteomes.
Liang Wang, Jianye Yang, Yue Huang, Qinghua Liu, Yaping Xu, Xue Piao, Michael J. Wise   +6 more
doaj   +1 more source

Metabolic Pathway Analysis: Advantages and Pitfalls for the Functional Interpretation of Metabolomics and Lipidomics Data. [PDF]

Biomolecules, 2023
Tsouka S, Masoodi M.
europepmc   +1 more source

Transcriptome Profiling and Chlorophyll Metabolic Pathway Analysis Reveal the Response of Nitraria tangutorum to Increased Nitrogen. [PDF]

Plants (Basel), 2023
Liu C, Duan N, Chen X, Li X, Zhao N, Cao W, Li H, Liu B, Tan F, Zhao X, Li Q.   +10 more
europepmc   +1 more source

Correction: Metabolic pathway analysis of hyperuricaemia patients with hyperlipidaemia based on high-throughput mass spectrometry: a case-control study. [PDF]

Lipids Health Dis, 2023
Wei X, Jia X, Liu R, Zhang S, Liu S, An J, Zhou L, Zhang Y, Mo Y, Li X.   +9 more
europepmc   +1 more source

Differential Gene Expression and Metabolic Pathway Analysis of Cladophora rupestris under Pb Stress Conditions. [PDF]

Int J Environ Res Public Health, 2022
Liu L, Zhang L, Zhao L, Chen Q, Zhang Q, Cao D, Liu Z.   +6 more
europepmc   +1 more source