Results 111 to 120 of about 1,277,321 (205)

Modeling energy depletion in rat livers using Nash equilibrium metabolic pathway analysis. [PDF]

Sci Rep, 2022
Lucia A, Ferrarese E, Uygun K.
europepmc   +1 more source

Circulating metabolites and bladder cancer: a Mendelian randomization and multi-omics study

Discover Oncology
Background The mechanisms by which various circulating metabolites influence bladder cancer (BLCA) progression via differentially expressed metabolic pathway genes remain unclear.
Zhe Chang, Jirong Wang, Li Wang, Zongjian Hu, Siyu Chen, Li Yang   +5 more
doaj   +1 more source

Urine Metabolomics of Gout Reveals the Dynamic Reprogramming and Non-Invasive Biomarkers of Disease Progression

Metabolites
Background/Objectives: Gout, a complex metabolic disorder of increasing global incidence, remains incompletely understood in its pathogenesis. Current diagnostic approaches exhibit significant limitations, including insufficient specificity and the ...
Guizhen Zhu, Yuan Luo, Nan Su, Xiangyi Zheng, Zhusong Mei, Qiao Ye, Jie Peng, Peiyu An, Yangqian Song, Weina Luo, Hongxia Li, Guangyun Wang, Haitao Zhang   +12 more
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Computational Identification of Essential Enzymes as Potential Drug Targets in Shigella flexneri Pathogenesis Using Metabolic Pathway Analysis and Epitope Mapping. [PDF]

J Microbiol Biotechnol, 2021
Narad P, Himanshu, Bansal H.
europepmc   +1 more source

Integrated gene-metabolite association network analysis reveals key metabolic pathways in gastric adenocarcinoma

Heliyon
Gastric adenocarcinoma is one of the most death cause cancers worldwide. Metabolomics is an effective approach for investigating the occurrence and progression of cancer and detecting prognostic biomarkers by studying the profiles of small bioactive ...
Botao Xu, Yuying Shi, Chuang Yuan, Zhe Wang, Qitao Chen, Cheng Wang, Jie Chai   +6 more
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Comparative metabolomics reveals specific metabolic signatures in colorectal cancer cell line models

Discover Oncology
Colorectal cancer (CRC) exhibits substantial metabolic heterogeneity, which plays a critical role in tumor progression and treatment response. However, systematic comparisons of metabolic profiles among widely used CRC cell lines are still lacking ...
Manshan Li, Chuanyang Yu, Zhihua Li, Lianjie Xiong, Jiaru Wang, Xingyu Shang, Hehong Sun, Yanhong Chang, Xinxin Du, Ran Zheng   +9 more
doaj   +1 more source

Learning motif features and topological structure of molecules for metabolic pathway prediction

Journal of Cheminformatics
Metabolites serve as crucial biomarkers for assessing disease progression and understanding underlying pathogenic mechanisms. However, when the metabolic pathway category of metabolites is unknown, researchers face challenges in conducting metabolomic ...
Jianguo Hu, Yiqing Zhang, Jinxin Xie, Zhen Yuan, Zhangxiang Yin, Shanshan Shi, Honglin Li, Shiliang Li   +7 more
doaj   +1 more source

Integrative Metabolic Pathway Analysis Reveals Novel Therapeutic Targets in Osteoarthritis. [PDF]

Mol Cell Proteomics, 2020
Rocha B, Cillero-Pastor B, Eijkel G, Calamia V, Fernandez-Puente P, Paine MRL, Ruiz-Romero C, Heeren RMA, Blanco FJ.   +8 more
europepmc   +1 more source

Metabolic Pathway Analysis and Effectiveness of Tamoxifen in Danish Breast Cancer Patients. [PDF]

Cancer Epidemiol Biomarkers Prev, 2020
Ahern TP, Collin LJ, Baurley JW, Kjærsgaard A, Nash R, Maliniak ML, Damkier P, Zwick ME, Isett RB, Christiansen PM, Ejlertsen B, Lauridsen KL, Christensen KB, Silliman RA, Sørensen HT, Tramm T, Hamilton-Dutoit S, Lash TL, Cronin-Fenton D.   +18 more
europepmc   +1 more source

Comparative Analysis of Metabolic Pathways

Comparative Analysis of Metabolic Pathways
Supervisor:Kenji Satou 知識科学研究科 博士 identifier:https://dspace.jaist.ac.jp/dspace/handle/10119 ...
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