Results 171 to 180 of about 1,277,321 (205)
Some of the next articles are maybe not open access.
Metabolic Pathway Analysis of Saccharomyces Cerevisiae
2005In metabolic engineering, analysis of pathways is central and it involves quantification of pathway fluxes and how these fluxes are controlled. Therefore metabolic pathway analysis rely on metabolic control analysis and metabolic flux analysis. This paper introduces the basic concepts of metabolic pathway analysis that serves as a valuable analytical ...
Simon Ostergaard +2 more
openaire +1 more source
Combinatorial Complexity of Pathway Analysis in Metabolic Networks
Molecular Biology Reports, 2002Elementary flux mode analysis is a promising approach for a pathway-oriented perspective of metabolic networks. However, in larger networks it is hampered by the combinatorial explosion of possible routes. In this work we give some estimations on the combinatorial complexity including theoretical upper bounds for the number of elementary flux modes in ...
Steffen, Klamt, Jörg, Stelling
openaire +2 more sources
Metabolic Pathway Analysis Employing Bioinformatic Software
2018Metabolomics can be defined as the entire content of metabolites in a system and their roles and interactions in various metabolic pathways reflecting the genetic information encrypted in a genome. Of late, various biochemical and metabolic studies are being applied for monitoring the dynamics of growth and development of model plants.
Soma S. Marla +2 more
openaire +1 more source
Pathway Activity Profiling (PAPi): A Tool for Metabolic Pathway Analysis
2014Pathway Activity Profiling (PAPi) is a method developed to correlate levels of metabolites to the activity of metabolic pathways operating within biological systems. Based solely on a metabolomics data set and the Kyoto Encyclopedia of Genes and Genomes, PAPi predicts and compares the activity of metabolic pathways across experimental conditions, which
openaire +2 more sources
On-line metabolic pathway analysis based on metabolic signal flow diagram
Biotechnology and Bioengineering, 1998In this work, an integrated modeling approach based on a metabolic signal flow diagram and cellular energetics was used to model the metabolic pathway analysis for the cultivation of yeast on glucose. This approach enables us to make a clear analysis of the flow direction of the carbon fluxes in the metabolic pathways as well as of the degree of ...
H, Shi, K, Shimizu
openaire +2 more sources
Understanding the Roadmap of Metabolism by Pathway Analysis
2006The theoretical investigation of the structure of metabolic systems has recently attracted increasing interest. In this chapter, the basic concepts of metabolic pathway analysis are described and various applications are outlined. In particular, the concepts of nullspace and elementary flux modes are explained.
Stefan, Schuster +2 more
openaire +2 more sources
Metabolic pathway analysis of the xylose-metabolizing yeast protoplast fusant ZLYRHZ7
Journal of Bioscience and Bioengineering, 2017Xylose is the second major fermentable sugar present in hard woods and herbs (after d-glucose). Therefore, efficient conversion of xylose to ethanol is essential for the commercialization of lignocellulosic ethanol, which may provide an ideal alternative to fossil fuels in the future.
Jingping, Ge +4 more
openaire +2 more sources
Increasing the flux in metabolic pathways: A metabolic control analysis perspective
Biotechnology and Bioengineering, 1998The problems of engineering increased flux in metabolic pathways are analyzed in terms of the understanding provided by metabolic control analysis. Over-expression of a single enzyme is unlikely to be effective unless it is known to have a high flux control coefficient, which can be used as an approximate predictive tool.
openaire +2 more sources
Co-expression Analysis of Metabolic Pathways in Plants
2009Co-expression analysis allows experimenters to re-use archived expression microarray data to uncover previously unknown functional relationships between genes. An observation that a group of genes are co-expressed across diverse experimental conditions suggests they may play similar roles in the cell.
openaire +2 more sources
Metabolic pathway analysis of tumors using stable isotopes
Seminars in Cancer BiologyMetabolic reprogramming is pivotal in malignant transformation and cancer progression. Tumor metabolism is shaped by a complex interplay of both intrinsic and extrinsic factors that are not yet fully elucidated. It is of great value to unravel the complex metabolic activity of tumors in patients.
Qiufen, Bi +3 more
openaire +2 more sources