Results 21 to 30 of about 1,277,321 (205)
The protein cost of metabolic fluxes: prediction from enzymatic rate laws and cost minimization [PDF]
, 2016 Bacterial growth depends crucially on metabolic fluxes, which are limited by the cell's capacity to maintain metabolic enzymes. The necessary enzyme amount per unit flux is a major determinant of metabolic strategies both in evolution and bioengineering.
Bar-Even, Arren +5 more
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Quantifying Dynamic Regulation in Metabolic Pathways with Nonparametric Flux Inference [PDF]
, 2019 One of the central tasks in systems biology is to understand how cells regulate their metabolism. Hierarchical regulation analysis is a powerful tool to study this regulation at the metabolic, gene-expression, and signaling levels.
He, Fei, Stumpf, Michael P H
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Bioinformatic Approaches to Metabolic Pathways Analysis [PDF]
, 2011 The growth and development in the last decade of accurate and reliable mass data collection techniques has greatly enhanced our comprehension of cell signaling networks and pathways. At the same time however, these technological advances have also increased the difficulty of satisfactorily analyzing and interpreting these ever-expanding datasets.
Stuart, Maudsley +5 more
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NetFlow: A tool for isolating carbon flows in genome-scale metabolic networks
Metabolic Engineering Communications, 2021 1. Abstract: Genome-scale stoichiometric models (GSMs) have been widely utilized to predict and understand cellular metabolism. GSMs and the flux predictions resulting from them have proven indispensable to fields ranging from metabolic engineering to ...
Sean G. Mack, Ganesh Sriram
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Analysis and comparison of metabolic pathway databases [PDF]
Briefings in Bioinformatics, 2001 Enormous amounts of data result from genome sequencing projects and new experimental methods. Within this tremendous amount of genomic data 30-40 per cent of the genes being identified in an organism remain unknown in terms of their biological function.
U, Wittig, A, De Beuckelaer
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Stoichiometry Based Steady-State Hepatic Flux Analysis: Computational and Experimental Aspects
Metabolites, 2012 The liver has many complex physiological functions, including lipid, protein and carbohydrate metabolism, as well as bile and urea production. It detoxifies toxic substances and medicinal products. It also plays a key role in the onset and maintenance of
Mehmet A. Orman +4 more
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Computing the shortest elementary flux modes in genome-scale metabolic networks [PDF]
, 2009 This article is available open access through the publisher’s website through the link below. Copyright @ The Author 2009.Motivation: Elementary flux modes (EFMs) represent a key concept to analyze metabolic networks from a pathway-oriented perspective ...
Acuña +54 more
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Metabolites, 2023 Yams are economic and medicinal crops with a long growth cycle, spanning between 9–11 months due to their prolonged tuber dormancy. Tuber dormancy has constituted a major constraint in yam production and genetic improvement.
Jeremiah S. Nwogha +7 more
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On the estimation of metabolic profiles in metagenomics [PDF]
, 2013 Metagenomics enables the characterization of the specific metabolic potential of a microbial community. The common approach towards a quantitative representation of this potential is to count the number of metagenomic sequence fragments that can be ...
, Meinicke, Peter
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Metabolic pathway analysis web service (Pathway Hunter Tool at CUBIC) [PDF]
Bioinformatics, 2004 Abstract Motivation: Pathway Hunter Tool (PHT), is a fast, robust and user-friendly tool to analyse the shortest paths in metabolic pathways. The user can perform shortest path analysis for one or more organisms or can build virtual organisms (networks) using enzymes.
S A, Rahman +4 more
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