Results 31 to 40 of about 1,277,321 (205)

Fructose metabolism in Chromohalobacter salexigens: interplay between the Embden–Meyerhof–Parnas and Entner–Doudoroff pathways [PDF]

open access: yes, 2019
Background The halophilic bacterium Chromohalobacter salexigens metabolizes glucose exclusively through the Entner–Doudoroff (ED) pathway, an adaptation which results in inefficient growth, with significant carbon overflow, especially at low salinity ...
Argandoña Bertrán, Montserrat   +12 more
core   +1 more source

Pathway Analysis and Metabolic Engineering in Corynebacterium glutamicum [PDF]

open access: yesBiological Chemistry, 2000
The gram-positive bacterium Corynebacterium glutamicum is used for the industrial production of amino acids, e.g. of L-glutamate and L-lysine. During the last 15 years, genetic engineering and amplification of genes have become fascinating methods for studying metabolic pathways in greater detail and for the construction of strains with the desired ...
Sahm, H., Eggeling, L., de Graaf, A. A.
openaire   +3 more sources

gapseq: informed prediction of bacterial metabolic pathways and reconstruction of accurate metabolic models

open access: yesGenome Biology, 2021
Genome-scale metabolic models of microorganisms are powerful frameworks to predict phenotypes from an organism’s genotype. While manual reconstructions are laborious, automated reconstructions often fail to recapitulate known metabolic processes. Here we
Johannes Zimmermann   +2 more
doaj   +1 more source

High-Coverage Serum Metabolomics Reveals Metabolic Pathway Dysregulation in Diabetic Retinopathy: A Propensity Score-Matched Study

open access: yesFrontiers in Molecular Biosciences, 2022
Background: Diabetic retinopathy (DR) is a major diabetes-related disease linked to metabolism. However, the cognition of metabolic pathway alterations in DR remains scarce.
Chengnan Guo   +27 more
doaj   +1 more source

Structural Kinetic Modeling of Metabolic Networks [PDF]

open access: yes, 2006
To develop and investigate detailed mathematical models of cellular metabolic processes is one of the primary challenges in systems biology. However, despite considerable advance in the topological analysis of metabolic networks, explicit kinetic ...
B. Blasius   +19 more
core   +2 more sources

Prognostic value and co-expression patterns of metabolic pathways in cancers

open access: yesBMC Genomics, 2020
Background Abnormal metabolic pathways have been considered as one of the hallmarks of cancer. While numerous metabolic pathways have been studied in various cancers, the direct link between metabolic pathway gene expression and cancer prognosis has not ...
Dan Zhang, Yan Guo, Ni Xie
doaj   +1 more source

Alterations in Pattern Baldness According to Sex: Hair Metabolomics Approach

open access: yesMetabolites, 2021
Pattern baldness has been associated with the male hormone, dihydrotestosterone. In this study, we tried to determine how the overall metabolic pathways of pattern baldness differ in patients and in normal controls.
Yu Ra Lee   +4 more
doaj   +1 more source

A genome scale metabolic network for rice and accompanying analysis of tryptophan, auxin and serotonin biosynthesis regulation under biotic stress [PDF]

open access: yes, 2013
Background Functional annotations of large plant genome projects mostly provide information on gene function and gene families based on the presence of protein domains and gene homology, but not necessarily in association with gene expression or ...
Amarasinghe, V.   +8 more
core   +2 more sources

Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry [PDF]

open access: yes, 2011
This work describes a freely available web-based facility which can be used to analyse raw or processed mass spectrometric data from metabolomics experiments and display the metabolites identified – and changes in their experimental abundance – in the ...
Barrett, M.P.   +3 more
core   +2 more sources

Mechanism of the Effect of Compound Anoectochilus roxburghii (Wall.) Lindl. Oral Liquid in Treating Alcoholic Rat Liver Injury by Metabolomics

open access: yesDrug Design, Development and Therapy, 2023
Tingxuan Huang, Youjia Wu, Lingyi Huang, Renyi Lin, Zhenyue Li, Xiaoxiao Wang, Pingping Wu, Liying Huang School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, People’s Republic of ChinaCorrespondence: Liying Huang; Pingping Wu, School of ...
Huang T   +7 more
doaj  

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