Results 41 to 50 of about 1,277,321 (205)
AIMS Microbiology, 2018 Traditional biochemical research has resulted in a good understanding of many aspects of metabolism. However, this reductionist approach is time consuming and requires substantial resources, thus raising the question whether modern metabolomics and ...
Diana M. Downs +4 more
doaj +1 more source
Automation on the generation of genome scale metabolic models [PDF]
, 2012 Background: Nowadays, the reconstruction of genome scale metabolic models is a non-automatized and interactive process based on decision taking. This lengthy process usually requires a full year of one person's work in order to satisfactory collect ...
de Córdoba, P. Fernández +6 more
core +1 more source
Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. [PDF]
, 2014 Human diets differ from those of non-human primates. Among few obvious differences, humans consume more meat than most non-human primates and regularly cook their food.
Blekhman, Ran +5 more
core +2 more sources
A Shift in Central Metabolism Accompanies Virulence Activation in Pseudomonas aeruginosa. [PDF]
, 2020 The availability of energy has significant impact on cell physiology. However, the role of cellular metabolism in bacterial pathogenesis is not understood.
Chacko, Jenu V +4 more
core +1 more source
Metabolomics reveals key resistant responses in tomato fruit induced by Cryptococcus laurentii
Food Chemistry: Molecular Sciences, 2022 To investigate the mechanisms underlying inducible resistance in postharvest tomato fruit, non-targeted metabolome analysis was performed to uncover metabolic changes in tomato fruit upon Cryptococcus laurentii treatment.
Qiong Tang +4 more
doaj +1 more source
Metabolic Modulation Predicts Heart Failure Tests Performance [PDF]
, 2019 The metabolic changes that accompany changes in Cardiopulmonary testing (CPET) and heart failure biomarkers (HFbio) are not well known. We undertook metabolomic and lipidomic phenotyping of a cohort of heart failure (HF) patients and utilized Multiple ...
Abbate, Antonio +11 more
core +3 more sources
Frontiers in EndocrinologyBackgroundPathologically, metabolic disorder plays a crucial role in polycystic ovarian syndrome (PCOS). However, there is no conclusive evidence lipid metabolite levels to PCOS risk.MethodsIn this study, genome-wide association study (GWAS) genetic data
Xinzhe Wang +6 more
doaj +1 more source
Machine Learning Methods for Analysis of Metabolic Data and Metabolic Pathway Modeling
Metabolites, 2018 Machine learning uses experimental data to optimize clustering or classification of samples or features, or to develop, augment or verify models that can be used to predict behavior or properties of systems. It is expected that machine learning will help
Miroslava Cuperlovic-Culf
doaj +1 more source
Augmenting Biogas Process Modeling by Resolving Intracellular Metabolic Activity [PDF]
, 2019 The process of anaerobic digestion in which waste biomass is transformed to methane by complex microbial communities has been modeled for more than 16 years by parametric gray box approaches that simplify process biology and do not resolve intracellular ...
Denny Popp +7 more
core +1 more source
Elementary mode analysis: a useful metabolic pathway analysis tool for characterizing cellular metabolism [PDF]
Applied Microbiology and Biotechnology, 2009 Elementary mode analysis is a useful metabolic pathway analysis tool to identify the structure of a metabolic network that links the cellular phenotype to the corresponding genotype. The analysis can decompose the intricate metabolic network comprised of highly interconnected reactions into uniquely organized pathways.
Cong T, Trinh +2 more
openaire +2 more sources