Results 211 to 220 of about 78,835 (252)

Phenotyping and Genotyping of Drug Metabolism to Guide Pharmacotherapy in Psychiatry

Current Drug Delivery, 2013
In psychiatry, around 130 drugs are available which have been detected and developed during the last 60 years. These drugs are effective and essential for the treatment of many psychiatric disorders and symptoms. Therapeutic outcomes, however, are still far from satisfactory for many patients.
Christoph, Hiemke, Mohamed, Shams
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Drug-Metabolizing Enzymes and Therapeutic Drug Monitoring in Psychiatry

Therapeutic Drug Monitoring, 1996
The multiplicity of the drug-metabolizing cytochrome P450 system was discovered 20 years ago. During the past 10 years the complementary DNAs of the most important P450 enzymes have been cloned and sequenced, and much has been learned about their substrate specificities, selective inhibitors, and functional characteristics. Cytochrome P4501A2 (CYP1A2),
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Impact of a Metabolic Screening Bundle on Rates of Screening for Metabolic Syndrome in a Psychiatry Resident Outpatient Clinic

Academic Psychiatry, 2012
Although it is widely acknowledged that second-generation antipsychotics are associated with cardiometabolic side effects, rates of metabolic screening have remained low. The authors created a quality-improvement (QI) intervention in an academic medical center outpatient psychiatry resident clinic with the aim of improving rates of screening for ...
Ilse R, Wiechers, Mark, Viron, Joseph, Stoklosa, Oliver, Freudenreich, David C, Henderson, Anthony, Weiss   +5 more
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[Metabolic diseases in psychiatry].

Tijdschrift voor psychiatrie, 2016
Metabolic diseases can be associated with psychiatric symptoms. We present two case histories that demonstrate the importance of correctly diagnosing a metabolic disease as being the cause of psychiatric symptoms. We also discuss which symptoms or signals may indicate a metabolic disease.
M G M, De Sain-Van der Velden, J J, Jans, M, Figee, M, Engelen, H C M T, Prinsen, N M, Verhoeven-Duif, A B P, van Kuilenburg, G, Visser, C H, Vinkers   +8 more
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Pharmacogenomics in Psychiatry: Antidepressant Metabolism

2019
Antidepressants are metabolized by many of the CYP450 enzyme systems. There is usually more than 1 pathway of metabolism of a medication, usually consisting of a major pathway and some minor ones. Data show that polymorphisms affect the blood levels of medications.
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Medical Research Council Unit for Metabolic Studies in Psychiatry, Sheffield

Psychological Medicine, 1973
The Medical Research Council Unit for Metabolic Studies in Psychiatry was set up at Middle-wood Hospital, Sheffield, in 1967. It was to a considerable extent a continuation of the Medical Research Council Unit for the Chemical Pathology of Mental Disorders which had been associated with the Department of Physiology in the University of Birmingham under
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Targeting Drug Metabolism in Psychiatry: Pharmacogenetic Insights into CYP2D6 and CYP2C19

Current Pharmacogenomics and Personalized Medicine
Introduction:: Pharmacogenetics is revolutionising psychiatric care by providing insights into how genetic variants, particularly in CYP2D6 and CYP2C19, affect drug metabolism, efficacy, and side effects. These insights help clinicians tailor treatment for drugs such as SSRIs, tricyclic antidepressants, and ...
Darshan Gowda Bharathi Srinivasa, Prashant Tiwari, Sunil Kumar Kadiri   +2 more
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[The basics of metabolic psychiatry].

Psychiatria Hungarica : A Magyar Pszichiatriai Tarsasag tudomanyos folyoirata
The stability of brain functions is mainly determined by the energy management of the cells, and mental health is, therefore, profoundly affected by metabolic dysfunctions and immune and inflammatory processes. Research sheds light on more and more details and connections about the efficacy of diet and exercise, based on which we can develop effective ...
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[The first successes of the immuno-metabolic track in precision psychiatry].

Medecine sciences : M/S
Psychiatric disorders are associated with a high prevalence of cardiovascular and metabolic risk factors such as diabetes, obesity, and metabolic syndrome, as well as specific symptoms: hyperphagia, weight gain, hypersomnia, fatigue, and anhedonia.
Ophélia, Godin, Ariel, Frajerman, Aiste, Lengvenyte, Jeremy, Bernard, Ana C, Andreazza, Bruno, Etain, Marion, Leboyer   +6 more
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[Health promotion in psychiatry and mental health: The example of metabolic syndrome and nursing practices].

Recherche en soins infirmiers, 2022
Introduction : Life expectancy in psychiatric patients is reduced by 15 to 20 years due to the presence of comorbidities and the lifestyle of these patients. Metabolic syndrome, also a side effect of antipsychotic drugs, is an aggravating factor of this phenomenon, which is why health promotion is essential.
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