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Metabolic Syndrome in Child and Adolescent Psychiatry

Psychiatric Annals, 2020
In adults, metabolic syndrome (MetS) is defined as a constellation of at least 3 of 5 cardiometabolic risk factors: central obesity, hyperglycemia, elevated blood pressure, elevated triglycerides, and decreased high-density lipoprotein cholesterol.
Zheala Qayyum   +2 more
exaly   +2 more sources

Phenotyping and Genotyping of Drug Metabolism to Guide Pharmacotherapy in Psychiatry

Current Drug Delivery, 2013
In psychiatry, around 130 drugs are available which have been detected and developed during the last 60 years. These drugs are effective and essential for the treatment of many psychiatric disorders and symptoms. Therapeutic outcomes, however, are still far from satisfactory for many patients.
Christoph, Hiemke, Mohamed, Shams
openaire   +2 more sources

Drug-Metabolizing Enzymes and Therapeutic Drug Monitoring in Psychiatry

Therapeutic Drug Monitoring, 1996
The multiplicity of the drug-metabolizing cytochrome P450 system was discovered 20 years ago. During the past 10 years the complementary DNAs of the most important P450 enzymes have been cloned and sequenced, and much has been learned about their substrate specificities, selective inhibitors, and functional characteristics. Cytochrome P4501A2 (CYP1A2),
openaire   +2 more sources

Impact of a Metabolic Screening Bundle on Rates of Screening for Metabolic Syndrome in a Psychiatry Resident Outpatient Clinic

Academic Psychiatry, 2012
Although it is widely acknowledged that second-generation antipsychotics are associated with cardiometabolic side effects, rates of metabolic screening have remained low. The authors created a quality-improvement (QI) intervention in an academic medical center outpatient psychiatry resident clinic with the aim of improving rates of screening for ...
Ilse R, Wiechers   +5 more
openaire   +2 more sources

[Metabolic diseases in psychiatry].

Tijdschrift voor psychiatrie, 2016
Metabolic diseases can be associated with psychiatric symptoms. We present two case histories that demonstrate the importance of correctly diagnosing a metabolic disease as being the cause of psychiatric symptoms. We also discuss which symptoms or signals may indicate a metabolic disease.
M G M, De Sain-Van der Velden   +8 more
openaire   +1 more source

Pharmacogenomics in Psychiatry: Antidepressant Metabolism

2019
Antidepressants are metabolized by many of the CYP450 enzyme systems. There is usually more than 1 pathway of metabolism of a medication, usually consisting of a major pathway and some minor ones. Data show that polymorphisms affect the blood levels of medications.
openaire   +1 more source

Medical Research Council Unit for Metabolic Studies in Psychiatry, Sheffield

Psychological Medicine, 1973
The Medical Research Council Unit for Metabolic Studies in Psychiatry was set up at Middle-wood Hospital, Sheffield, in 1967. It was to a considerable extent a continuation of the Medical Research Council Unit for the Chemical Pathology of Mental Disorders which had been associated with the Department of Physiology in the University of Birmingham under
openaire   +2 more sources

Prevalence of obesity, metabolic syndrome, diabetes and risk of cardiovascular disease in a psychiatric inpatient sample: results of the Metabolism in Psychiatry (MiP) Study

European Archives of Psychiatry and Clinical Neuroscience, 2019
The information on prevalence of obesity, diabetes, metabolic syndrome (MetS) and cardiovascular risk (CVR) and on sociodemographic variables available in patients with psychiatric diseases about to be treated with weight gain-associated medication (e.g., clozapine, mirtazapine, quetiapine) is limited.
Richard Musil, Barbara B Barton
exaly   +3 more sources

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