Results 51 to 60 of about 1,241,146 (293)

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green, Brenda Colella, Alana Changoor, David J. Mikulis, Adrienne Li, Kadeen Johns, Georges A. Monette   +6 more
wiley   +1 more source

A 6-week ketogenic diet in treatment-resistant depression: a prospective single-arm feasibility pilot trial

Frontiers in Nutrition
BackgroundPrior evidence for the ketogenic diet (KD) interventions in treatment-resistant depression (TRD) was very limited when recruitment for the present pilot trial began on 1 November 2023.
Cemre Cukaci, Cemre Cukaci, Ulrich Rabl, Ulrich Rabl, Ulrich Rabl, Richard Frey, Richard Frey, Richard Frey   +7 more
doaj   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Ketones and their essential role in the developing brain☆

Oilseeds and fats, crops and lipids
The human brain is energetically expensive in adults but even more so during early development. Current models of human brain energy metabolism remain largely glucocentric, with ketone bodies, mainly acetoacetate and β-hydroxybutyrate, often framed as ...
Cholette-Tétrault Samuel, LeBlanc Piette Adrien, Fernandes Karl, Zemmour Kevin, Cunnane Stephen C.   +4 more
doaj   +1 more source

Insomnia disorders are associated with increased cardiometabolic disturbances and death risks from cardiovascular diseases in psychiatric patients treated with weight-gain-inducing psychotropic drugs: results from a Swiss cohort

BMC Psychiatry, 2022
Study objectives Insomnia disorders as well as cardiometabolic disorders are highly prevalent in the psychiatric population compared to the general population.
Nermine Laaboub, Céline Dubath, Setareh Ranjbar, Guibet Sibailly, Claire Grosu, Marianna Piras, Didier Délessert, Hélène Richard-Lepouriel, Nicolas Ansermot, Severine Crettol, Frederik Vandenberghe, Carole Grandjean, Aurélie Delacrétaz, Franziska Gamma, Kerstin Jessica Plessen, Armin von Gunten, Philippe Conus, Chin B. Eap   +17 more
doaj   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

Core psychiatry

, 2012
A new edition of a highly successful, award winning textbook for trainee psychiatrists, covering in one volume all the subjects required for the new MRCPsych and similar exams.
Wright, Padraig, Phelan, Michael, Stern, Julian   +2 more
core   +3 more sources

Advances and challenges in development of precision psychiatry through clinical metabolomics on mood and psychotic disorders

, 2020
Metabolomics is defined as the study of the global metabolite profile in a system under a given set of conditions. The objective of this review is to comprehensively assess the literature on metabolomics in mood disorders and schizophrenia and provide ...
Cao, Bing, McIntyre, Roger S., Tasic, Ljubica, Brietzke, Elisa, Hayashi, Mirian A. F., Mansur, Rodrigo B., Cerqueira, Raphael O., Pedrini, Mariana, Silva Nani, Joao Victor   +8 more
core   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Transdiagnostic remission of psychiatric comorbidity in post-traumatic stress disorder, ADHD, and binge-eating disorder using ketogenic metabolic therapy: a retrospective case report

Frontiers in Nutrition
BackgroundPsychiatric comorbidities, including post-traumatic stress disorder (PTSD), ADHD, and binge-eating disorder (BED), frequently share overlapping symptoms and metabolic dysfunctions.
Erin L. Bellamy, Nicole Laurent
doaj   +1 more source