Results 51 to 60 of about 3,909,262 (243)

Parent-offspring transmission of adipocytokine levels and their associations with metabolic traits [PDF]

, 2011
Adipose tissue secreted cytokines (adipocytokines) have significant effects on the physiology and pathology of human metabolism relevant to diabetes and cardiovascular disease. We determined the relationship of the pattern of these circulating hormones
Nasser M. Al-Daghri, Alkharfy Khalid M., Shaun B Sabico, Omar S. Al-Attas, Khalid M. Alkharfy, Kumar Sudhesh, Sabico, Shaun, Sudhesh Kumar, George P Chrousos, Omar S Al-Attas, Alokail, Majed S., Shaun B. Sabico, Al-Attas, Omar S., Al-Attas Omar S., Majed S. Alokail, Al-Daghri, Nasser M., Greg C Gibson, Sabico Shaun B., Greg C. Gibson, Majed S Alokail, Sobhy M. Yakout, Gibson, Greg, Yakout Sobhy M., Al-Daghri Nasser M., Chrousos, George P., Alokail Majed S., Kumar, Sudhesh, Nasser M Al-Daghri, Yakout, Sobhy M., Gibson Greg C., Sobhy M Yakout, Chrousos George P., Alkharfy, Khalid M., George P. Chrousos, Khalid M Alkharfy   +34 more
core   +2 more sources

A clinician’s guide to understanding resistance to thyroid hormone due to receptor mutations in the TRα and TRβ isoforms

Clinical Diabetes and Endocrinology, 2017
There are two genes that express the major thyroid hormone receptor isoforms. Mutations in both these genes have given rise to Resistance to Thyroid Hormone (RTH) syndromes (RTHβ, RTHα) that can have variable phenotypes for mutations of the same receptor
Brijesh K. Singh, Paul M. Yen
doaj   +1 more source

Revealing the Variation and Stability of Bacterial Communities in Tomato Rhizosphere Microbiota

Microorganisms, 2020
Microorganisms that colonize the plant rhizosphere can contribute to plant health, growth and productivity. Although the importance of the rhizosphere microbiome is known, we know little about the underlying mechanisms that drive microbiome assembly and ...
Zhiqiang Cheng, Shaonan Lei, Ye Li, Wei Huang, Rongqin Ma, Juan Xiong, Ting Zhang, Lingyue Jin, Hafeez ul Haq, Xiaohong Xu, Baoyu Tian   +10 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Amino Acid Metabolism in Liver Mitochondria: From Homeostasis to Disease

Metabolites
Hepatic mitochondria play critical roles in sustaining systemic nutrient balance, nitrogen detoxification, and cellular bioenergetics. These functions depend on tightly regulated mitochondrial processes, including amino acid catabolism, ammonia clearance
Ranya Erdal, Kıvanç Birsoy, Gokhan Unlu   +2 more
doaj   +1 more source

5-Methylindole Potentiates Aminoglycoside Against Gram-Positive Bacteria Including Staphylococcus aureus Persisters Under Hypoionic Conditions

Frontiers in Cellular and Infection Microbiology, 2020
Antibiotic resistance/tolerance has become a severe threat to human and animal health. To combat antibiotic-resistant/tolerant bacteria, it is of significance to improve the efficacy of traditional antibiotics.
Fengqi Sun, Mengmeng Bian, Zhongyan Li, Boyan Lv, Yuanyuan Gao, Yuanyuan Gao, Yan Wang, Xinmiao Fu, Xinmiao Fu   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Characterization of extracellular and membrane potentials in imeglimin‐treated islets

Journal of Diabetes Investigation
Glucose‐stimulated insulin secretion (GSIS) in β cells depends critically on membrane depolarization–induced Ca2+ influx. Accordingly, the electrophysiological assessment of intact islets, where β cells act as functional syncytia, is essential for ...
Asuka Tsurumoto, Ryota Inoue, Esther Ong Yajima, Meng Zou, Junyu Luo, Takahiro Tsuno, Emi Ishida, Kohichi Matsunaga, Jun Shirakawa   +8 more
doaj   +1 more source

Analysis of the community composition and bacterial diversity of the rhizosphere microbiome across different plant taxa

MicrobiologyOpen, 2019
Rhizobacteria play an important role in bridging the soil and plant microbiomes and improving the health and growth of plants. In this study, the bacterial community structures and compositions of rhizosphere microbiomes associated with six plant species,
Shaonan Lei, Xiaohong Xu, Zhiqiang Cheng, Juan Xiong, Rongqin Ma, Lanlan Zhang, Xiaorong Yang, Yunxi Zhu, Binghuo Zhang, Baoyu Tian   +9 more
doaj   +1 more source

The coupled photocycle of phenyl-p-benzoquinone and Light-Harvesting Complex II (LHCII) within the biohybrid system

Scientific Reports, 2022
The combination of trimeric form of the light-harvesting complex II (LHCII3), a porous graphite electrode (GE), and the application of phenyl-p-benzoquinone (PPBQ), the quinone derivative, allow the construction of a new type of biohybrid photoactive ...
Magdalena Łazicka, Adriana Palińska-Saadi, Paulina Piotrowska, Bohdan Paterczyk, Radosław Mazur, Magdalena Maj-Żurawska, Maciej Garstka   +6 more
doaj   +1 more source