Results 31 to 40 of about 3,909,262 (243)

Screening for functional IRESes using α-complementation system of β-galactosidase in Pichia pastoris

open access: yesBiotechnology for Biofuels, 2019
Background Pichia pastoris is becoming a promising chassis cell for metabolic engineering and synthetic biology after its whole genome and transcriptome sequenced. However, the current systems for multigene co-expression in P. pastoris are not efficient.
Yide Huang   +5 more
doaj   +1 more source

Metabolic responses of primary and transformed cells to intracellular Listeria monocytogenes. [PDF]

open access: yes, 2012
The metabolic response of host cells, in particular of primary mammalian cells, to bacterial infections is poorly understood. Here, we compare the carbon metabolism of primary mouse macrophages and of established J774A.1 cells upon Listeria monocytogenes
Wolfgang Eisenreich (108576)   +14 more
core   +1 more source

Effects of single- and mixed-bacterial inoculation on the colonization and assembly of endophytic communities in plant roots

open access: yesFrontiers in Plant Science, 2022
The introduction and inoculation of beneficial bacteria in plants have consistently been considered as one of the most important ways to improve plant health and production.
Ting Zhang   +9 more
doaj   +1 more source

Electricity network regulation in the EU : The challenges ahead‎ for transmission and distribution

open access: yes, 2018
The UK model of incentive regulation of power grids was at one time the most advanced, and elements of it were adopted throughout the EU. This model worked well, particularly in the context of limited investment and innovation, a single and strong ...

core   +1 more source

Metabolic control through the PGC-1 family of transcription coactivators [PDF]

open access: yes, 2005
Many complex biological programs are controlled at the level of gene transcription by DNA binding transcription factors. Recent studies have revealed a novel mode of regulation by coactivator proteins, best illustrated by the PGC-1 family of coactivators.
Lin, J.   +8 more
core   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Inter-organ metabolic feedback via BCAA catabolism regulates glucagon-like hormone secretion in Drosophila

open access: yesNature Communications
Metabolic homeostasis regulated by nutrient-responsive endocrine hormones is essential for organismal survival. In insects, lipid and carbohydrate mobilization is controlled by adipokinetic hormone (Akh), a glucagon-like peptide secreted from ...
Takashi Nishimura   +2 more
doaj   +1 more source

Orphan Enzymes in the Mammalian L-Fucose Degradation Pathway

open access: yesBiomolecules
Orphan enzymes are recognized and classified enzymatic activities that lack associated amino acid sequences. Since the term was coined in the mid-2000s, the proportion of orphan enzymes has substantially decreased; however, it is estimated that at least ≈
Apolonia Witecka   +6 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Differential Effects of Two Fermentable Carbohydrates on Central Appetite Regulation and Body Composition [PDF]

open access: yes, 2012
Background: Obesity is rising at an alarming rate globally. Different fermentable carbohydrates have been shown to reduce obesity. The aim of the present study was to investigate if two different fermentable carbohydrates (inulin and β-glucan) exert ...
Ruey Leng Loo   +96 more
core   +1 more source

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