Results 161 to 170 of about 4,435,982 (345)

High Serum miR-421 is Associated with Metabolic Dysregulation and Inflammation in Patients with Metabolic Syndrome

, 2021
Aécio Assunção Braga, Raul Hernandes Bortolin, Magda Elizabeth Graciano-Saldarriaga, Thiago Dominguez Crespo Hirata, Álvaro Cerda, Renata Caroline Costa de Freitas, Hui Tzu Lin‐Wang, Jéssica Bassani Borges, João Ítalo Dias França, Laureane Nunes Masi, Rui Curi, Tânia Cristina Pithon‐Curi, Marcelo Ferraz Sampaio, Lara Reinel de Castro, Gisele Medeiros Bastos, Rosário Dominguez Crespo Hirata, Mário Hiroyuki Hirata   +16 more
openalex   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men.

Journal of the American Medical Association (JAMA), 2002
H. Lakka, D. Laaksonen, T. Lakka, L. Niskanen, E. Kumpusalo, J. Tuomilehto, J. Salonen   +6 more
semanticscholar   +1 more source

Effects of barley species on parameters related to metabolic syndrome in mice

, 2013
Sachina Suzuki, Yoshikazu Takanami, Seichiro Aoe   +2 more
openalex   +2 more sources

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Cardiovascular morbidity and mortality associated with the metabolic syndrome.

Diabetes Care, 2001
B. Isomaa, P. Almgren, T. Tuomi, B. Forsén, Kaj Lahti, M. Nissen, M. Taskinen, L. Groop   +7 more
semanticscholar   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Anthropometric measurements as a potential non-invasive alternative for the diagnosis of metabolic syndrome in adolescents

, 2019
Silmara Salete de Barros Silva Mastroeni, Marco Fábio Mastroeni, John Paul Ekwaru, Solmaz Setayeshgar, Paul J. Veugelers, Muryel de Carvalho Gonçalves, Patrícia Helen de Carvalho Rondó   +6 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Supplementary Material for: Improved Identification and Antihypertension Pharmacotherapy in Cardiorenal Metabolic Syndrome: Focus on Racial/Ethnic Minorities, Olmesartan Medoxomil, and Combination Therapy

, 2012
Keith C. Ferdinand
openalex   +1 more source