Results 51 to 60 of about 4,485,385 (359)

Rare diseases leading to childhood Glaucoma. epidemiology, pathophysiogenesis, and management [PDF]

, 2015
Noteworthy heterogeneity exists in the rare diseases associated with childhood glaucoma. Primary congenital glaucoma is mostly sporadic; however, 10% to 40% of cases are familial. CYP1B1 gene mutations seem to account for 87% of familial cases and 27% of
Abdolrahimzadeh, Solmaz, CONTESTABILE, Maria Teresa, FAMELI, VALERIA, Mollo, Roberto, Perdicchi, Andrea, RECUPERO, Santi Maria   +5 more
core   +3 more sources

Obesity, metabolic syndrome, and primary hypertension

Pediatric nephrology (Berlin, West), 2020
Primary hypertension is the dominant form of arterial hypertension in adolescents. Disturbed body composition with, among other things, increased visceral fat deposition, accelerated biological maturation, metabolic abnormalities typical for metabolic ...
M. Litwin, Z. Kułaga
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Fabrication and application of cisplatin-loaded mesoporous magnetic nanobiocomposite: a novel approach to smart cervical cancer chemotherapy

Cancer Nanotechnology, 2022
There are significant challenges in developing drug carriers for therapeutic perspective. We have investigated a novel nanocarrier system, based on combining functionalized magnetic nanocomposite with Metal–Organic Frameworks (MOFs).
Mahdieh Darroudi, Seyedeh Elnaz Nazari, Fereshteh Asgharzadeh, Nima Khalili-Tanha, Ghazaleh Khalili-Tanha, Toktam Dehghani, Maryam Karimzadeh, Mina Maftooh, Gordon A. Fern, Amir Avan, Majid Rezayi, Majid Khazaei   +11 more
doaj   +1 more source

Active commuting is associated with a lower risk of obesity, diabetes and metabolic syndrome in Chilean adults [PDF]

, 2017
Background: There is limited evidence on how active commuting is associated with health benefits in developing countries. The aim of this study therefore was to investigate the associations between active commuting and markers of adiposity and ...
Aguilar-Farias, Nicolás, Alvarez, Cristian, Celis-Morales, Carlos A., Cristi-Montero, Carlos, Díaz-Martínez, Ximena, Floody, Pedro Delgado, Garrido-Méndez, Alex, Leiva, Ana María, Martínez, María Adela, Petermann, Fanny, Poblete-Valderrama, Felipe, Ramirez-Campillo, Rodrigo, Rodríguez, Fernando, Salas-Bravo, Carlos, Steell, Lewis, Willis, Naomi D.   +15 more
core   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

The relationship between daytime napping and obesity: a systematic review and meta-analysis

Scientific Reports, 2023
Daytime napping, a habit widely adopted globally, has an unclear association with obesity. In this study, we executed a meta-analysis to explore the relationship between daytime napping and obesity.
Zixin Cai, Yan Yang, Jingjing Zhang, Yu Liu   +3 more
doaj   +1 more source

The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies

Diabetology & Metabolic Syndrome, 2020
BackgroundThe prevalence of metabolic syndrome varies among populations with different ethnicities. Asian populations develop metabolic complications at lower amounts of adiposity than western populations.
F. S. Sigit, D. Tahapary, S. Trompet, E. Sartono, K. Willems van Dijk, F. Rosendaal, R. de Mutsert   +6 more
semanticscholar   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

The therapeutic potential of Wild Bitter Melon to ameliorate muscle atrophy in a murine model [PDF]

Avicenna Journal of Phytomedicine
Objective: Muscle atrophy due to immobility is a common complication of many diseases and a consequence of therapeutic processes. Immobility and inactivity have been shown to be associated with increased inflammation.
Sima Seifi, Seyedeh Elnaz Nazari, Amir Avan, Nima Khalili-tanha, Fatemeh Babaei, Saman Soleimanpour, Fereshteh Asgharzadeh, Mousa-al-reza Hajzadeh, Majid Khazaei, Abdoljalal Marjani   +9 more
doaj   +1 more source