Results 271 to 280 of about 1,033,501 (330)
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Cyclic AMP metabolism in fragile X syndrome

Annals of Neurology, 1992
AbstractCyclic AMP (cAMP) metabolism was studied in platelets from a series of 14 patients with fragile X syndrome (fra X) and 21 control individuals. 1‐Isobutyl‐3‐methylxanthine was used to inhibit phosphodiesterase and thus measure cAMP production, prostaglandin E1 was used to assess receptor‐mediated cAMP accumulation, and forskolin was used to ...
E, Berry-Kravis, P R, Huttenlocher
openaire   +2 more sources

Retinoid X Receptor Heterodimers in the Metabolic Syndrome

New England Journal of Medicine, 2005
The principal abnormalities of the metabolic syndrome are abdominal obesity, atherogenic dyslipidemia, hypertension, insulin resistance, inflammation, and prothrombotic states.
Andrew I, Shulman, David J, Mangelsdorf
openaire   +4 more sources

Rosiglitazone improves insulin resistance, lipid profile and promotes adiposity in a genetic model of metabolic syndrome X.

Folia biologica, 2002
RSG is a member of the TZD group of drugs widely used in treatment of type 2 diabetes. The underlying mechanism of TZD action in insulin-sensitive tissues is not fully understood. In this study we show that 14-day RSG administration in a new rodent model
Ondřej Šeda   +3 more
semanticscholar   +1 more source

Metabolic syndrome X: a review.

The Canadian journal of cardiology, 2000
Metabolic syndrome X is a multifaceted syndrome, which occurs frequently in the general population. It is more common in men than in women. A large segment of the adult population of industrialized countries develops the metabolic syndrome, produced by genetic, hormonal and lifestyle factors such as obesity, physical inactivity and certain nutrient ...
O, Timar, F, Sestier, E, Levy
openaire   +1 more source

Adult fragile X syndrome: Neuropsychology, brain anatomy, and metabolism

American Journal of Medical Genetics, 1995
AbstractTo understand the implications of suboptimal gene expression in fragile X syndrome [fra(X)], we sought to define the central nervous abnormalities in fra(X) syndrome to determine if abnormalities in specific brain regions or networks might explain the cognitive and behavioral abnormalities in this syndrome.
Schapiro, M. B.   +11 more
openaire   +3 more sources

Molecular mechanism of vascular disease in metabolic syndrome X

Journal of Diabetes and its Complications, 2002
Syndrome X is a clinical syndrome in which multiple risks are clustered in an individual and is a common basis of vascular disease in the industrial countries. However, the molecular basis of syndrome X has not been elucidated. We have analyzed body fat distribution using CT scanning and have shown that accumulated intra-abdominal visceral fat is ...
Yuji, Matsuzawa   +2 more
openaire   +2 more sources

SYNDROME X

The Nurse Practitioner, 1996
Recent trends in the American lifestyle, such as a high-fat diet and inactivity, have promoted the emergence of a metabolic disorder titled syndrome X. Although originally linked to non-insulin-dependent diabetes mellitus (NIDDM) and characterized by insulin resistance, syndrome X is now better described as a cascade of disorders encompassing not only ...
L E, Minchoff, J A, Grandin
openaire   +2 more sources

Metabolic Syndrome X: A Postmenopausal Woman's Hidden Nemesis

Journal of Women & Aging, 1997
ABSTRACT Metabolic syndrome X is a combination of modifiable (physiological, morphological, lifestyle) and non-modifiable (genotype, sex, age, race) risk factors that are likely precursors to non-insulin dependent diabetes mellitus (NIDDM) and cardiovascular disease (CVD), two of the top ten killers of postmenopausal women.
Lynda B. Ransdell   +2 more
openaire   +1 more source

Myocardial Metabolism in Cardiac Syndrome X

1999
Patients with normal coronary arteries who experience chest pain have constituted an enigma for many years. As some of these patients have ischemia-like ST segment depression in response to exercise stress testing attempts have been made to ascertain whether the syndrome has an ischemic etiology.
openaire   +1 more source

Molecular Mechanism of Metabolic Syndrome X: Contribution of Adipocytokines · Adipocyte‐derived Bioactive Substances

Annals of the New York Academy of Sciences, 1999
Y. Matsuzawa   +2 more
semanticscholar   +1 more source

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