Results 41 to 50 of about 342,953 (254)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Profile of healthy female students in Syria: Investigation on anthropometric, lifestyle, and dietary characteristics, along with hematological and plasma biochemical parameters

Cogent Medicine, 2016
In Syria, a Mediterranean country, health risk data on young women are limited. The aim of study: is to evaluate lifestyle factors, along with biomarkers related to cardiovascular risk factors in a group of university female students.
Nada Dehneh, Mazen Rajab, Wafika Zarzour, Muhidien Jouma   +3 more
doaj   +1 more source

Turkish Adult Risk Factor Study survey 2012: overall and coronary mortality and trends in the prevalence of metabolic syndrome

Türk Kardiyoloji Derneği Arşivi, 2013
Objectives: We aimed to analyze 1) overall and coronary mortality findings in the Turkish Adult Risk Factor (TARF) study survey 2012 and 2) the temporal trends in prevalence of metabolic syndrome (MetS) and its distribution across seven geographic ...
Altan Onat, Murat Yüksel, Bayram Köroğlu, H. Ali Gümrükçüoğlu, Mesut Aydın, H. Altuğ Çakmak, Ahmet Karagöz, Günay Can   +7 more
doaj   +1 more source

Impact of Menopausal Status, Metabolic Syndrome and its Risk Factors on Impaired Quality of Life above Middle-aged Women [PDF]

Korean Journal of Women Health Nursing, 2016
PURPOSE: This study explored influencing factors on quality of life (QoL) above middle-aged women in relation to demographic factors, health-related factors, menopausal status, metabolic syndrome (MS) and its risk factors.
Jisoon Kim, Sukhee Ahn
doaj   +1 more source

Markers of cognitive function in individuals with metabolic disease: Morquio Syndrome and Tyrosinemia Type III [PDF]

, 2018
We characterized cognitive function in two metabolic diseases. MPS–IVa (mucopolysaccharidosis IVa, Morquio) and tyrosinemia type III individuals were assessed using tasks of attention, language and oculomotor function.
Blundell, James, Chakrapani, Anupam, Frisson, S., Gissen, Paul, Hendriksz, Chris, Kearney, Shauna, MacDonald, Anita, Olson, Andrew, Vijay, Suresh   +8 more
core   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The frequency of metabolic syndrome in patients with the subclinical hypothyroidism [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. An increased cardiovascular risk of thyroid dysfunction is associated with the impairment of lipid and lipoprotein metabolism, endothelial dysfunction, metabolic, hormonal, hemodynamic changes and coagulation disorders.
Mulić Mersudin, Skrijeljm Fadil, Hajrović Šefcet, Prelević Rade, Milev Boško   +4 more
doaj   +1 more source

Relation of C-reactive protein to body fat distribution and features of the metabolic syndrome in Europeans and South Asians.

, 2001
OBJECTIVE: To investigate the association between circulating C-reactive protein (CRP) concentrations and indices of body fat distribution and the insulin resistance syndrome in South Asians and Europeans. DESIGN: : Cross-sectional study.
NG Forouhi, N Sattar, PM McKeigue, PM Ridker, PM Ridker, F Haverkate, W Koenig, MA Mendall, RP Tracy, JC Pickup, JS Yudkin, A Festa, PM McKeigue, PM McKeigue, PM McKeigue, JC Seidell, JR Patsch, J Highton, JP Després, AS Greenberg, T Chajek-Shaul, P Bjorntorp, P Ebeling, U Saxena   +23 more
core   +1 more source

Dietary fibre may mitigate sarcopenia risk:Findings from the NU-AGE cohort of older european adults [PDF]

, 2020
Sarcopenia is characterised by a progressive loss of skeletal muscle mass and physical function as well as related metabolic disturbances. While fibre-rich diets can influence metabolic health outcomes, the impact on skeletal muscle mass and function is ...
Battista, Giuseppe, Bazzocchi, Alberto, Berendsen, Agnes, de Groot, Lisette C.P.G.M., Fairweather-Tait, Susan, Feskens, Edith J.M., Franceschi, Claudio, Januszko, Olga, Jennings, Amy, Kadi, Fawzi, Montiel-Rojas, Diego, Nicoletti, Claudio, Nilsson, Andreas, Pietruszka, Barbara, Santoro, Aurelia   +14 more
core   +5 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source