Results 21 to 30 of about 3,734,782 (145)

Metabolic regulation of regulatory T cell development and function [PDF]

open access: yes, 2014
It is now well established that the effector T cell (Teff) response is regulated by a series of metabolic switches. Quiescent T cells predominantly require ATP-generating processes, whereas proliferating Teff require high metabolic flux through growth ...
Alves   +68 more
core   +2 more sources

Coordinated balancing of muscle oxidative metabolism through PGC-1α increases metabolic flexibility and preserves insulin sensitivity [PDF]

open access: yes, 2011
The peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) enhances oxidative metabolism in skeletal muscle. Excessive lipid oxidation and electron transport chain activity can, however, lead to the accumulation of harmful metabolites and ...
Handschin, C.   +3 more
core   +1 more source

TREM2-dependent effects on microglia in Alzheimer\u27s Disease [PDF]

open access: yes, 2018
Alzheimer’s disease (AD) is a late-onset dementia characterized by the deposition of amyloid plaques and formation of neurofibrillary tangles (NFTs) which lead to neuronal loss and cognitive deficits.
Colonna, Marco   +2 more
core   +3 more sources

The Markers Of Bone Metabolism And System Inflammation In Patients With Osteoarthritis Depending On Body Mass, The Influence Of Symptomatic Slow Acting Drugs [PDF]

open access: yes, 2016
Aim. To assess the levels of markers of the bone synthesis and system inflammation in patients with osteoarthritis (OA) in combination with obesity and their dynamic under the influence of basic treatment.Materials and methods.
Cherkasova, A. (Anna)   +1 more
core  

The expression of stlA in Photorhabdus luminescens is controlled by nutrient limitation [PDF]

open access: yes, 2013
Photorhabdus is a genus of Gram-negative entomopathogenic bacteria that also maintain a mutualistic association with nematodes from the family Heterorhabditis.
Bode, Helge Björn   +3 more
core   +11 more sources

Organellar carbon metabolism is co-ordinated with distinct developmental phases of secondary xylem [PDF]

open access: yes, 2019
Subcellular compartmentation of plant biosynthetic pathways in the mitochondria and plastids requires coordinated regulation of nuclear encoded genes, and the role of these genes has been largely ignored by wood researchers. In this study, we constructed
Fierro Gutierrez, Ana Carolina Elisa   +4 more
core   +2 more sources

Embryo metabolism : what does it really mean? [PDF]

open access: yes, 2015
The study of early embryo metabolism has fascinated researchers in the field for nearly a century. Herein, we give a brief account of the general features of embryo metabolism and some consideration of the research performed to reach such conclusions. It
Lewis, Niamh, Sturmey, Roger
core  

Application of recombinant DNA technology to studies on plant secondary metabolism [PDF]

open access: yes, 2001
This review which is concerned with the application of recombinant DNA technology to studies on plant secondary metabolism, presents the more common plant transformation strategies and shows how these genetic approaches are being used in attempts to ...
Yeoman, Michael M., Zárate, Rafael
core   +1 more source

Hypergraph models of metabolism [PDF]

open access: yes, 2014
In this paper, we employ a directed hypergraph model to investigate the extent to which environmental variability influences the set of available biochemical reactions within a living cell.
Chuzhanova, N, Crofts, JJ, Pearcy, N
core  

Different Effects of Maternal Low-Isoflavone Soy Protein and Genistein Consumption on Hepatic Lipid Metabolism of 21-Day-Old Male Rat Offspring. [PDF]

open access: yes, 2017
Amino acid composition and isoflavone are alleged contributors to the beneficial effects of soy protein isolate (SPI) on lipid metabolism. Therefore, we investigated the contributing component(s) of SPI in a maternal diet to the regulation of lipid ...
Han, Anna, Kwon, Young Hye, Won, Sae Bom
core   +3 more sources

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