Results 141 to 150 of about 2,075,060 (269)

The competition of amino acid among tumors, tumor-associated macrophages and T cells based on metabolic reprogramming. [PDF]

iScience
Xianyu C, Song Y, Zhao C, Min Q, Wang Z, Zhang M, Zhang B.   +6 more
europepmc   +1 more source

The Vocabulary of Metabolism [PDF]

Science, 1922
openaire   +2 more sources

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Metabolic Subtypes Predict Treatment Response in Acute Myeloid Leukemia: A Pilot Study. [PDF]

Blood Lymphat Cancer
Yan C, Huang Y, Cai Q, Li X, Yang Q, Feng G, Yang H, Chen Y, Hu J.   +8 more
europepmc   +1 more source

Metabolism of Acetaldehyde --- a Metabolic Branching Point. [PDF]

Acta Chemica Scandinavica, 1966
Kurt Nordström, Lisbeth Fries, Göran Bergson, L. Ehrenberg, J. Brunvoll, E. Bunnenberg, Carl Djerassi, Ruth Records   +7 more
openaire   +2 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Comparative Study on Biological Characteristics and Functions of Three Porcine-Derived Lactic Acid Bacteria. [PDF]

Animals (Basel)
Yu M, Li Y, Yu B, Chen D.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Genetic Association Between Sex Hormones, Serum Urate, and Gout: A Comprehensive Mendelian Randomization Study

International Journal of Endocrinology
Shiwei Li, Mengjuan Zhang, Xuemei Wang, Yadi Huang, Bo Huang, Meng Wang, Ming Liu, Jingqiu Cui   +7 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source