Characterizing Plasma-Based Metabolomic Signatures for Metastasis in Non-Small Cell Lung Cancer. [PDF]
Liu M+7 more
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Distinct metabolome and flux responses in the retinal pigment epithelium to cytokines associated with age-related macular degeneration: comparison of ARPE-19 cells and eyecups. [PDF]
Hansman DS+4 more
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Neurometabolite Alterations Associated With Cannabis Use: A Proton Magnetic Resonance Spectroscopy Meta-Analysis. [PDF]
Kirkland AE+4 more
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Integration of lipidomics and widely targeted metabolomics provides a comprehensive metabolic landscape of Poa pratensis under cadmium stress. [PDF]
Cui T, Wang Y, Niu K, Zhao C, Ma H.
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Cross-feeding creates tipping points in microbiome diversity. [PDF]
Clegg T, Gross T.
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Multi-omics technology reveals the changes in gut microbiota to stimulate aromatic amino acid metabolism in children with allergic rhinitis and constipation. [PDF]
Wang C+5 more
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Transport of Metabolites [PDF]
Transport phenomena have a fundamental role in cellular activity. The evidence of a limiting barrier is given by the fact that the content of living cells differs from that of the medium. In most cases the concentration of K+ in the cell is ten or more times higher than that of Na+, even in cells immersed in a medium where Na+ concentration exceeds K+.
O. Barnabei+3 more
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Metabolites of Demoxepam, a Chlordiazepoxide Metabolite, in Man
Journal of Pharmaceutical Sciences, 1972The biotransformation of demoxepam, 7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide, was studied in two subjects. Following the administration of a 20-mg. oral dose of demoxepam-2-14C, these subjects excreted 24 and 29% of the dose in the urine as unchanged drug. The urinary metabolites included “opened lactam” (formed by hydrolysis of
Morton A. Schwartz, Edward Postma
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The results of the animal experiment demonstrate that oxidative hydroxylation is the major mode of metabolism of phencyclidine. It is evident that this process takes place in all three rings of the molecule. Hydroxylation of the piperidyl moiety probably also accounts for the formation of the N-dealkylated metabolites.
K. Biemann, Lan K. Wong
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This handbook compiles authoritative information about fungal metabolites and their chemistry and biotechnology. The first in the reference work series “Phytochemicals”, and written by a team of international expert authors, this book provides reference information ranging from the description of fungal natural products, over their use e.g.
Merillon, Jean-Michel+1 more
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