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Acta Anaesthesiologica Scandinavica, 1997
Morphine is a potent opioid analgesic widely used for the treatment of acute pain and for long‐term treatment of severe pain. Morphine is a member of the morphinan‐framed alkaloids, which are present in the poppy plant. The drug is soluble in water, but its solubility in lipids is poor.In man, morphine‐3‐glucuronide (M3G) and morphine‐6‐glucu‐ronide ...
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Morphine is a potent opioid analgesic widely used for the treatment of acute pain and for long‐term treatment of severe pain. Morphine is a member of the morphinan‐framed alkaloids, which are present in the poppy plant. The drug is soluble in water, but its solubility in lipids is poor.In man, morphine‐3‐glucuronide (M3G) and morphine‐6‐glucu‐ronide ...
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Biological profile of the metabolites and potential metabolites of the anticonvulsant remacemide
Epilepsy Research, 1992Remacemide hydrochloride ((+/-)-2-amino-N-(1-methyl-1,2-diphenylethyl)- acetamide hydrochloride or FPL 1292AA) is a novel compound undergoing clinical trials for patients with generalized tonic/clonic and complex partial epilepsy. Remacemide exhibits efficacy against maximal electroconvulsive shock (MES) in rodents and seizures elicited by N-methyl-D,L-
George E. Garske+9 more
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Metabolite Profiling of Actinobacterial Metabolites [PDF]
Ramasamy Balagurunathan+4 more
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Advances in Metabolite Identification
Bioanalysis, 2011One of the central challenges to metabolomics is metabolite identification. Regardless of whether one uses so-called 'targeted' or 'untargeted' metabolomics, eventually all paths lead to the requirement of identifying (and quantifying) certain key metabolites.
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