Results 91 to 100 of about 1,002,608 (307)

Pharmacokinetics of torasemide and its metabolites in end-stage renal disease

, 1994
The pharmacokinetics of torasemide, a new loop diuretic, as well as its active metabolites M1 and M3, and its inactive main metabolite, M5, were studied in 12 patients with end-stage renal failure during single i.v.
Schwab, A., Strutz, F., Müller, G. A., Krämer, Bernhard K., Braun, N., Risler, T.   +5 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Plant secondary metabolites as defenses, regulators, and primary metabolites: the blurred functional trichotomy

, 2020
The plant kingdom produces hundreds of thousands of low molecular weight organic compounds. Based on the assumed functions of these compounds, the research community has classified them into three overarching groups: primary metabolites, which are ...
Erb, Matthias, Daniel J. Kliebenstein, Kliebenstein, Daniel J., Matthias Erb   +3 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Retraction: Carulli, L. et al. The OMICs Window into Nonalcoholic Fatty Liver Disease (NAFLD). Metabolites 2019, 9(2), 25

Metabolites, 2019
As the authors of the title paper [...]
Lucia Carulli, Giulia Zanca, Filippo Schepis, Erica Villa, Metabolites Editorial Office   +4 more
doaj   +1 more source

Microbial Virulence Factors, Antimicrobial Resistance Genes, Metabolites, and Synthetic Chemicals in Cabins of Commercial Aircraft

, 2023
Passengers are at a higher risk of respiratory infections and chronic diseases due to microbial exposure in airline cabins. However, the presence of virulence factors (VFs), antimicrobial resistance genes (ARGs), metabolites, and chemicals are yet to be ...
Zailina Hashim, Zhang, Xin,, Yuan, Yiwen,, Mei Zhang, Chen, Yang, Zhao, Zhuohui,, Norbäck, Dan,, Dan Norbäck, Fu, Xi, Zhang, Mei,, Zhao, Zhuohui, Norbäck, Dan, Xi Fu, Yu Sun, Ou, Zheyuan, Hashim, Zailina, Jamal Hisham Hashim, Zhang, Xin, Yiwen Yuan, Xin Zhang, Hashim, Zailina,, Zhang, Mei, Zhuohui Zhao, Fu, Xi,, Zheyuan Ou, Sun, Yu, Hashim, Jamal Hisham,, Yuan, Yiwen, Hashim, Jamal Hisham, Ou, Zheyuan,, Chen, Yang,, Sun, Yu,, Yang Chen   +32 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Isolation and Characterisation of Bacterial Metabolites as Potential Wood Preservatives

, 2012
The durability of wood has traditionally relied on the use of heavy metals and toxic compounds to deter wood degrading fungi. Conventional wood preservatives such as Chromated Copper Arsenate (CCA) have been widely used to control wood degrade for many ...
O'Callahan, Diahanna Rachelle
core  

Structure and biosynthesis of fungal secondary metabolites [PDF]

, 2013
The root rot pathogen Heterobasidion annosum s.l., i.e. H. abietinum, H. parviporum, H. annosum s.s., H. irregulare and H. occidentale, and the biocontrol fungus Phlebiopsis gigantea were investigated regarding their secondary metabolites.
Hansson, David
core  

Secondary metabolites in plant defence mechanisms

, 1994
Many secondary metabolites found in plants have a role in defence against herbivores, pests and pathogens. In this review, a few examples are described and discussed, and some of the problems in determining the precise role(s) df such metabolites ...
Wallsgrove, R. M., Bennett, R. N.
core   +1 more source