Results 91 to 100 of about 1,153,518 (297)

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Detection of 191 Taxifolin Metabolites and Their Distribution in Rats Using HPLC-ESI-IT-TOF-MSn

, 2016
Taxifolin is a ubiquitous bioactive constituent of foods and herbs. To thoroughly explore its metabolism in vivo, an HPLC-ESI-IT-TOF-MSn method combined with specific metabolite detection strategy was used to detect and identify the metabolites of ...
Ming-Ying Shang, Shao-Qing Cai, Feng Xu, Hong-Fu Li, Yi Wang, Ping Yang, Xuan Wang, Guang-Xue Liu, Feng-Chun Li   +8 more
core   +1 more source

Bioactive secondary metabolites from the endophytic fungus Chaetomium sp. isolated from Salvia officinalis growing in Morocco [PDF]

, 2009
This study reports the chemical investigation and cytotoxic activity of the secondary metabolites produced by the endophytic fungus Chaetomium sp. isolated from Salvia officinalis growing in Morocco. This plant was collected from the Beni-Mellal Mountain
Mueller, W.E.G., Hakikj, Adbelhak, Proksch, Peter, Ebel, R., Mosaddak, Mahjouba, Aly, Amal H., Edrada-Ebel, RuAngelie, Debbab, Adbessamad   +7 more
core   +4 more sources

Retraction: Carulli, L. et al. The OMICs Window into Nonalcoholic Fatty Liver Disease (NAFLD). Metabolites 2019, 9(2), 25

Metabolites, 2019
As the authors of the title paper [...]
Lucia Carulli, Giulia Zanca, Filippo Schepis, Erica Villa, Metabolites Editorial Office   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Antifungal Secondary Metabolites Against Blast Fungus Magnaporthe oryzae

, 2022
Magnaporthe oryzae is one of the most destructive fungal pathogen causing blast diseases in at least 50 grass species including wheat and rice. Although there has been comprehensive study on the fungicidal control of blast diseases, the development of ...
Islam, Tofazzal, Chakraborty, Moutoshi
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Changes in metabolites during an oral glucose tolerance test in early and mid-pregnancy : Findings from the PEARLS randomized, controlled lifestyle trial

, 2020
The oral glucose tolerance test (OGTT) is used to diagnose gestational and other types of diabetes. We examined metabolite changes during an OGTT, and how a comprehensive diet and physical activity intervention may influence these changes in a population
Kaumudi Joshipura, Martinez, Marijulie, Liang, Liming, Palacios, Cristina, Paul W. Franks, Trak-Fellermeier, Maria A., Shilpa N. Bhupathiraju, Maria A. Trak-Fellermeier, Bhupathiraju, Shilpa N., Danielle E. Haslam, Franks, Paul W., Li, Jun, Liming Liang, Haslam, Danielle E., Jun Li, Cristina Palacios, Joshipura, Kaumudi, Marijulie Martinez, Bhupathiraju, Shilpa N.,, Martinez, Marijulie,, Franks, Paul W.,, Liang, Liming,, Palacios, Cristina,, Joshipura, Kaumudi,, Trak-Fellermeier, Maria A.,, Li, Jun,, Lund University., Haslam, Danielle E.,   +27 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source