Results 131 to 140 of about 1,153,518 (297)
Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li +17 more
wiley +1 more source
Food Chemistry AdvancesThe study assessed the peptidomic profile of in-bag dry-aged (2 °C, RH 75 %, 0.5 m.s−1, n = 30) and wet-aged (-1.5 °C, n = 30) lamb with high and low levels of lipid oxidation.
Renyu Zhang +8 more
doaj +1 more source
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Arthritis Care &Research, EarlyView.Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Sulfur Metabolites in the North Pacific Subtropical Gyre and Transition Zone
, 2021 Sulfur is an essential nutrient for life and a constituent of many important biomolecules. Phytoplankton in the surface ocean use assimilatory reduction pathways to reduce inorganic sulfur, primarily in the form of sulfate (SO4 2-), into the necessary
Wood, Leland
core
Advanced Functional Materials, EarlyView.Establishment of bidirectional communication behavior between natural and artificial cells. The first type of communication from natural dendritic cells to artificial polymeric cells was achieved via ATP release after cell lysis. The released ATP was taken up via gated UV‐controlled permeability increase of the polymeric membrane for performing ...
Ilona Kalte +6 more
wiley +1 more source
Fiber‐Based Wearable Electronics as Adaptive Biointerfaces for Healthcare Applications
Advanced Functional Materials, EarlyView.Fiber‐based wearable electronics have been extensively studied as adaptive healthcare biointerfaces. In this review, we classify and introduce fiber‐based systems according to biointerface design, conductive materials, transduction mechanisms, and healthcare applications, and provide a perspective on their translation toward reliable, continuous ...
Sangwoo Hong +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande +9 more
wiley +1 more source
Identification of essential metabolites in metabolite networks
, 2012 Metabolite essentiality is an important topic in systems biology and as such there has been increased focus on their prediction in metabolic networks. Specifically, two related questions have become the focus of this field: how do we decrease the amount of gene knock-out workloads and is it possible to predict essential metabolites in different growth ...
openaire +1 more source
Measuring Blood Plasma Glutamine Levels Using a Nanopore‐Based Sensor
Advanced Healthcare Materials, EarlyView.Glutamine (GLN) is a biomarker useful for predicting toxic ammonia accumulation. Here, we used a biosensor based on the Cytolysin A (ClyA) nanopore coupled with the GLN‐specific protein substrate‐binding domain 2 (SBD2) to demonstrate real‐time measurement of GLN in blood plasma, highlighting the potential for future point‐of‐care applications ...
Sofia B. Relvas +9 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko +7 more
wiley +1 more source