Results 271 to 280 of about 2,167,847 (388)

Identification of bioactive metabolites using activity metabolomics

Nature reviews. Molecular cell biology, 2019
Markus M. Rinschen, J. Ivanisevic, M. Giera, G. Siuzdak   +3 more
semanticscholar   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

Lifestyle behaviors, serum metabolites and high myopia: Mendelian randomization and mediation analysis. [PDF]

Int J Ophthalmol
Liu NE, Xu XT, Yu XB.
europepmc   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Secondary metabolism of <i>Microcystis</i>: current understanding and recent advances in unlocking genomic and chemical diversity. [PDF]

Appl Environ Microbiol
Yancey CE, Hart LN, Dick GJ.
europepmc   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Identifying Key Metabolites in South African Medicinal Plants Using Dual Electrospray Ionization Metabolomics. [PDF]

Plants (Basel)
Makhafola MA, Naidoo CM, Obi CL, Iweriedor BC, Olaokun OO, Prinsloo E, Zubair MS, Mkolo NM.   +7 more
europepmc   +1 more source

Analysis of inositol metabolites produced by Saccharomyces cerevisiae in response to glucose stimulation.

, 1993
Phillip T. Hawkins, Len Stephens, John Piggott   +2 more
openalex   +1 more source

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

Nature, 2017
Dylan Dodd, M. Spitzer, W. V. Treuren, Bryan D. Merrill, A. J. Hryckowian, S. Higginbottom, Anthony T. Le, T. Cowan, G. Nolan, M. Fischbach, J. Sonnenburg   +10 more
semanticscholar   +1 more source

Long‐Term Elevated CO2 Improves Soil Health and Rice Yields in Paddy Fields

Advanced Science, EarlyView.
Combining the two longest‐running rice free‐air CO2 enrichment experiments with a global data synthesis, this study demonstrates that long‐term elevated CO2 consistently enhances soil health. In rice paddies, this improvement sustains the CO2 fertilization effect over decades.
Fan Jiang, Wenchao Du, Kees Jan van Groenigen, Josep Peñuelas, Scott X. Chang, Lian Song, Chuang Cai, Yu Wang, Lin Deng, Zhengkun Hu, Weishou Shen, Qicong Wu, Haiyang Yu, Ying Yin, Fuxun Ai, Wei Zhou, Dongming Wang, Jianqiang Sun, Xiaoyuan Yan, Renfang Shen, Jiabao Zhang, Hongyan Guo, Chunwu Zhu   +22 more
wiley   +1 more source