Results 71 to 80 of about 1,126 (284)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Nutritional value of glycerin for pigs determined by different methodologies

Revista Brasileira de Zootecnia
The objective of this study was to determine the nutritional value of glycerin for pigs using different inclusion levels of this test ingredient and the methodologies of total collection and chromium oxide marker.
Guiomar Helena Verussa, Anderson Corassa, Douglas dos Santos Pina, Ana Paula Silva Ton, Cláudia Marie Komiyama, Alexandre de Oliveira Teixeira   +5 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Energy dynamics of broiler in thermoneutral or heat stress environments with different levels of metabolizable energy [PDF]

Ciência Rural
: Two experiments evaluated the effect of different levels of metabolizable energy (ME) on nutrient metabolizability, energy balance, and broiler performance under thermoneutral and cyclic heat stress conditions.
Maurício de Paula Ferreira Teixeira, Kamilla Ribas Soares, Ricardo Reis e Silva, Luiz Felipe Pinho Pereira, Cristiano Werneck Rocha Gondim, Mariana André Pompeu, Thiago Pajeú Nascimento, Nelson Carneiro Baião, Leonardo José Camargos Lara   +8 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Nutritional value of Brazilian distillers dried grains with solubles for pigs as determined by different methods

Revista Brasileira de Zootecnia
The objective of this study was to determine the digestibility coefficient (DC) of nutrients and the digestible energy (DE), and metabolizable energy (ME) values of distillers dried grains with solubles (DDGS) produced in Brazil by different methods ...
Anderson Corassa, Iziz Paula Anhõn da Silva Lautert, Douglas dos Santos Pina, Charles Kiefer, Ana Paula Silva Ton, Claudia Marie Komiyama, Alessandro Borges Amorim, Alexandre de Oliveira Teixeira   +7 more
doaj   +1 more source

Measurement of digestible and metabolizable energy of diets for rats [PDF]

Laboratory Animals, 1976
A balance method for the measurement of digestible and metabolizable energy in rats is described. Experimentally determined metabolizable energies of 2 diets for rats were closer to those values for metabolizable energy calculated from tabulated values for pigs rather than chickens.
B A, Rolls, S N, Hegde, M E, Coates
openaire   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Metabolizable energy and digestible amino acids of full-fat soybean without or with protease supplementation in diets for broilers

Ciência e Agrotecnologia
Two experiments were carried out to determine the energy values and the true ileal digestibility of amino acids of nine toasted full-fat soybeans (FFSB), without or with the addition of monocomponent protease.
Felipe Santos Dalólio, Luiz Fernando Teixeira Albino, Horácio Santiago Rostagno, Diego Ladeira da Silva, Maurílio de Lucas Xavier Júnior, Vinícius Duarte de Oliveira   +5 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source