Results 91 to 100 of about 584 (259)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Determination of the energetic value of corn, soybean meal and micronized full fat soybean for newly hatched chicks

open access: yesBrazilian Journal of Poultry Science, 2004
There are some evidences described in the literature showing reduced energy metabolizability of ingredients for newly hatched chicks. Hence, a metabolism trial was carried out with the objective of determining the metabolizable energy of corn grain ...
FA Longo   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Substituting Zinc Bacitracin Antibiotics with Symbiotics for Post-Peak Laying Hens

open access: yesBrazilian Journal of Poultry Science
The objective of this study was to evaluate the effect of adding symbiotics to the diet of laying hens in the post-peak laying period on performance variables, egg quality, and nutrient digestibility. One hundred and ninety-eight 70-week-old Dekalb White
DP Oliveira   +11 more
doaj   +1 more source

Moringa leaf meal in diets of slow-growing chickens on metabolizability, performance, carcass, organ biometry and meat colorimetry [PDF]

open access: yesRevista Brasileira de Saúde e Produção Animal
Two investigations were developed. The first experiment was to determine the metabolizability of Moringa (Moringa oleifera) leaf meal. 120 slow-growing, 21-day-old chickens were used.
José Virgilio Aguilar VÁSQUEZ   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

EFFECT OF RICE DISTILLER DRIED GRAIN WITH SOLUBLES ON GROWTH PERFORMANCE, NUTRIENTS METABOLIZABILITY AND HAEMATO-BIOCHEMISTRY IN BROILER CHICKEN [PDF]

open access: yesExploratory Animal and Medical Research
The present study was carried out to investigate the effect of dietary inclusion of rice distiller dried grain with solubles on growth performance, nutrients metabolizability and haemato-biochemistry in broiler chicken.
Bikas Ch. Debnath
doaj   +1 more source

The Amount of Metabolizable Glycine [PDF]

open access: yesAgricultural and Biological Chemistry, 1972
SUGAHARA, Michihiro, KANDATSU, Makoto
openaire   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy