Results 91 to 100 of about 1,743 (306)

Neurophysiological and behavioral studies of chimpanzees Semiannual report, Jan. 1 - Jun. 30, 1966 [PDF]

Techniques and bioinstrumentation for behavioral and neurophysiological studies of chimpanzees and Apollo ...
Adey, W. R., French, J. D.
core   +1 more source

Density-dependent switches in diet:a likely mechanism for negative feedbacks on goose population increase? [PDF]

, 2009
Goose grazing on arctic tundra vegetation has shown both positive and negative effects on subsequent foraging conditions. To understand the potential of a density-dependent feedback on herbivore population size, the relation between grazing pressure and ...
Kuijper, Dries Pieter Jan, Loonen, M. J. J. E., Ubels, R.   +2 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Food Metabolizability in Normal and Bluecomb Diseased Turkeys ,

Poultry Science, 1970
Abstract OF the lesions which have been observed in bluecomb diseased turkeys, most were located in the gastrointestinal (GI) tract (Jungherr and Pomeroy, 1965; Adams, 1969). Important alterations in GI function have also been shown to exist. These include a significant decrease in GI propulsive motility (Duke et al., 1969; Dziuk et al., 1969a) and a
G E, Duke, H E, Dziuk, O A, Evanson, D E, Nelson   +3 more
openaire   +2 more sources

Berechnung von gas- und partikelförmigen Emissionen aus der deutschen Landwirtschaft 1990-2015: Report zu Methoden und Daten (RMD) Berichterstattung 2017 [PDF]

, 2017
The report at hand (including a comprehensive annex of data) serves as additional document to the National Inventory Report (NIR) on the German green house gas emissions and the Informative Inventory Report (IIR) on the German emissions of air pollutants
Dämmgen, Ulrich, Döhler, Helmut, Döring, Ulrike, Eurich-Menden, Brigitte, Freibauer, Annette, Haenel, Hans-Dieter, Osterburg, Bernhard, Rösemann, Claus, Schreiner, Carsten, Wulf, Sebastian   +9 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Requerimientos nutricionales de cabras lecheras. II. Proteína metabolizable

Agronomía Mesoamericana, 2007
El objetivo de este trabajo es presentar un extracto de los requerimientos nutricionales de proteína metabolizable de cabras lecheras a partir de la reciente publicación del National Research Council (NRC 2007): Requerimientos Nutricionales de Pequeños Rumiantes: Ovejas, Cabras, Cérvidos y Camélidos del Nuevo Mundo, con el fi n de hacer esta ...
openaire   +7 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source