Results 91 to 100 of about 1,126 (284)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

The Metabolizable Energy of Wheat By-Products

open access: yesJournal of Applied Poultry Research, 1996
Abstract The composotion of wheat milling by-products varies markedly in different geographic regions among suppliers. In this study, the determined true metabolizable energy (TMEn) of 15 samples of wheat by-products, along with proximate composition and NDF, were investigated to develop prediction equations for estimating energy values.
openaire   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Enzyme complex at different levels in diets with enriched ingredients for commercial laying hens [PDF]

open access: yes, 2019
The objective of this study was to evaluate levels of inclusion of an enzyme complex (EC) in corn- and soybean meal-based diets for laying hens on the digestibility of nutrients and energy.
Cláudio José Parro de Oliveira   +23 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Temperatura ambiente e idade do frango de corte sobre o valor energético do milho

open access: yes, 2021
This study aimed to assess the effects of environmental temperature and age of broilers on the energy value of corn. A total of 288 Cobb 500 chicks were distributed in a complete randomized design with a split-plot arrangement and six replications of six
Fascina, Vitor Barbosa [UNESP]   +5 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Inclusion of maize distillers’ dried grains with solubles (DDGS) associated with the use of metabolisability-enhancing additives in the diet of laying quails [PDF]

open access: yesAnais da Academia Brasileira de Ciências
This study aimed to incorporate maize distillers’ dried grains with solubles (DDGS) into the diet of laying Japanese quail, along with two feed additives, xylanase and a metabolizability enhancer based on clay and algae.
MARCOS ADRIANO P. BARBOSA   +5 more
doaj   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Determination of the energetic value of corn, soybean meal and micronized full fat soybean for newly hatched chicks

open access: yesBrazilian Journal of Poultry Science, 2004
There are some evidences described in the literature showing reduced energy metabolizability of ingredients for newly hatched chicks. Hence, a metabolism trial was carried out with the objective of determining the metabolizable energy of corn grain ...
FA Longo   +6 more
doaj   +1 more source

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