Results 91 to 100 of about 584 (259)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
There are some evidences described in the literature showing reduced energy metabolizability of ingredients for newly hatched chicks. Hence, a metabolism trial was carried out with the objective of determining the metabolizable energy of corn grain ...
FA Longo +6 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Substituting Zinc Bacitracin Antibiotics with Symbiotics for Post-Peak Laying Hens
The objective of this study was to evaluate the effect of adding symbiotics to the diet of laying hens in the post-peak laying period on performance variables, egg quality, and nutrient digestibility. One hundred and ninety-eight 70-week-old Dekalb White
DP Oliveira +11 more
doaj +1 more source
Moringa leaf meal in diets of slow-growing chickens on metabolizability, performance, carcass, organ biometry and meat colorimetry [PDF]
Two investigations were developed. The first experiment was to determine the metabolizability of Moringa (Moringa oleifera) leaf meal. 120 slow-growing, 21-day-old chickens were used.
José Virgilio Aguilar VÁSQUEZ +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
EFFECT OF RICE DISTILLER DRIED GRAIN WITH SOLUBLES ON GROWTH PERFORMANCE, NUTRIENTS METABOLIZABILITY AND HAEMATO-BIOCHEMISTRY IN BROILER CHICKEN [PDF]
The present study was carried out to investigate the effect of dietary inclusion of rice distiller dried grain with solubles on growth performance, nutrients metabolizability and haemato-biochemistry in broiler chicken.
Bikas Ch. Debnath
doaj +1 more source
The Amount of Metabolizable Glycine [PDF]
SUGAHARA, Michihiro, KANDATSU, Makoto
openaire +1 more source
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

