Results 111 to 120 of about 1,126 (284)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Sixty four nulliparous rabbit does were divided into 4 groups, allocated to individual metabolic cages and fed (restricted or ad libitum) one of the following diets: C) 23% starch on DM; CP) 19% starch, based on Citrus Pulp; MM) 30% starch, based on ...
L. Bava +4 more
core +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Full fat rice bran processed by infrared in different time periods in broiler diets [PDF]
Trata-se de um estudo de metabolizabilidade em frangos de corte Cobb, para testar os benefícios do processamento térmico por infravermelho no farelo de arroz integral (FAI) em diferentes tempos (0, 6, 8 e 10min).
Ribeiro, Andrea Machado Leal +4 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
SUMMARY1. According to the Agricultural Research Council (1965) energy retention in cattle is predicted from metabolizable energy (ME) intake, the net availabilities of ME for maintenance (km) and for fattening (kf) and measurements made of fasting ...
J. S. Smith +2 more
core +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Objetivou-se avaliar a fitase combinada a ingestão de água com diferentes pH’s sobre o desempenho zootécnico e metabolizabilidade dos nutrientes de frangos na fase inicial (7 a 21 dias de idade). Foram utilizados 252 pintos de corte da linhagem comercial
Rondis, Carla Caroline de Souza Furiozo [UNESP]
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

