Results 111 to 120 of about 1,126 (284)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Energy utilization of diets with different starch content in nulliparous rabbit does fed different levels of intake

open access: yes, 2003
Sixty four nulliparous rabbit does were divided into 4 groups, allocated to individual metabolic cages and fed (restricted or ad libitum) one of the following diets: C) 23% starch on DM; CP) 19% starch, based on Citrus Pulp; MM) 30% starch, based on ...
L. Bava   +4 more
core   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Full fat rice bran processed by infrared in different time periods in broiler diets [PDF]

open access: yes, 2014
Trata-se de um estudo de metabolizabilidade em frangos de corte Cobb, para testar os benefícios do processamento térmico por infravermelho no farelo de arroz integral (FAI) em diferentes tempos (0, 6, 8 e 10min).
Ribeiro, Andrea Machado Leal   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Prediction of the Energy Requirements for Growth in Beef Cattle 1. The irrelevance of fasting metabolism

open access: yes, 1974
SUMMARY1. According to the Agricultural Research Council (1965) energy retention in cattle is predicted from metabolizable energy (ME) intake, the net availabilities of ME for maintenance (km) and for fattening (kf) and measurements made of fasting ...
J. S. Smith   +2 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Phytase combined with different pH’s of drinking water on the performance and metabolizability of nutrients in broilers in the initial phase

open access: yes
Objetivou-se avaliar a fitase combinada a ingestão de água com diferentes pH’s sobre o desempenho zootécnico e metabolizabilidade dos nutrientes de frangos na fase inicial (7 a 21 dias de idade). Foram utilizados 252 pintos de corte da linhagem comercial
Rondis, Carla Caroline de Souza Furiozo [UNESP]
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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