A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Performance and metabolizability in broilers fed diets containing rice bran and enzymatic complex
O Estado do Rio Grande do Sul é grande produtor de arroz, podendo utilizar os resíduos gerados nessa atividade para a alimentação animal. Dentre esses resíduos está o farelo de arroz (FA) com marcada presença de fatores antinutricionais.
Ledur, Vicente Santos
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Moringa leaf meal in diets of slow-growing chickens on metabolizability, performance, carcass, organ biometry and meat colorimetry [PDF]
Two investigations were developed. The first experiment was to determine the metabolizability of Moringa (Moringa oleifera) leaf meal. 120 slow-growing, 21-day-old chickens were used.
José Virgilio Aguilar VÁSQUEZ +5 more
doaj +1 more source
EFFECT OF RICE DISTILLER DRIED GRAIN WITH SOLUBLES ON GROWTH PERFORMANCE, NUTRIENTS METABOLIZABILITY AND HAEMATO-BIOCHEMISTRY IN BROILER CHICKEN [PDF]
The present study was carried out to investigate the effect of dietary inclusion of rice distiller dried grain with solubles on growth performance, nutrients metabolizability and haemato-biochemistry in broiler chicken.
Bikas Ch. Debnath
doaj +1 more source
The Amount of Metabolizable Glycine [PDF]
SUGAHARA, Michihiro, KANDATSU, Makoto
openaire +1 more source
The Metabolizable and Productive Energy of Carobs for the Growing Chick
Abstract THE pods of the carob tree (Ceraionia siliqua), popularly known as “St. John’s bread,” are fed to livestock and consumed by people in most Mediterranean countries. Recently they have been used outside this region in milk replacers for young calves (Robinson, 1960) and as an antidiarrhetic for babies (Pretorius and Venter, 1959). On the other
S, BORNSTEIN, B, LIPSTEIN, E, ALUMOT
openaire +2 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Metabolizable Energy of Rapeseed Meal for the Laying Hen
Abstract Sibbald and Slinger (1963) reported that, for chicks, the “corrected” metabolizable energy (M.E.) of solvent extracted rapeseed meal (R.M.) was about 1530 kilcalories per kilogram on an air-dry basis. Apparently, this is the only published estimate of the M.E. of R.M. In view of the current interest in the feeding potential of R.M.
openaire +2 more sources

