Results 121 to 130 of about 114,008 (316)

A microbiome and metabolomic signature of phases of cutaneous healing identified by profiling sequential acute wounds of human skin: An exploratory study.

PLoS ONE, 2020
Profiling skin microbiome and metabolome has been utilised to gain further insight into wound healing processes. The aims of this multi-part temporal study in 11 volunteers were to analytically profile the dynamic wound tissue and headspace metabolome ...
Mohammed Ashrafi, Yun Xu, Howbeer Muhamadali, Iain White, Maxim Wilkinson, Katherine Hollywood, Mohamed Baguneid, Royston Goodacre, Ardeshir Bayat   +8 more
doaj   +1 more source

Classification of participants in metabolome study in Eggua, Nigeria.

, 2018
Classification of participants in metabolome study in Eggua, Nigeria.
Raphael D. Isokpehi (4345231), Yogesh S. Shouche (70745), Bayatigeri Santhakumari (5155016), Olugbenga S. Onile (5155019), Atinuke M. Agunloye (4345237), Adewale S. Adebayo (4345240), Swapnil D. Mundhe (5155013), Chiaka I. Anumudu (4336099), Henrietta O. Awobode (5155010)   +8 more
core   +1 more source

PDHA1 Hyperactivation‐Mediated Glucose Metabolism Reprogramming Fuels Neutrophil NETosis and Promotes Acute Lung Injury

Advanced Science, EarlyView.
During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu, Wen‐Jing Zhong, Chen‐Yu Zhang, Meng‐Rui Chen, Nan‐Shi‐Yu Yang, Han‐Xi Sha, Yan‐Ling Qiu, Hui Chen, Jin‐Tong Yang, Li‐Ying Liang, Jian‐Bing Xiong, Shao‐Kun Liu, Cha‐Xiang Guan, Jia‐Xi Duan, Yong Zhou   +14 more
wiley   +1 more source

The Brain Metabolome of Male Rats across the Lifespan

, 2016
Comprehensive and accurate characterization of brain metabolome is fundamental to brain science, but has been hindered by technical limitations. We profiled the brain metabolome in male Wistar rats at different ages (day 1 to week 111) using high ...
Xie, Guoxiang, Chen, Tianlu, Zhao, Qing, Wang, Chongchong, Jia, Wei, Zhao, Aihua, Liu, Jiajian, Wang, Shouli, He, Zhigang, Zheng, Xiaojiao, Huang, Fengjie, Wang, Xiaoyan, Zhou, Mingmei, Panee, Jun   +13 more
core   +1 more source

Multi‐Omics Analyses Identify Candidate Genes Associated With Stage‐Specific Quality Formation in Mulching‐Treated Moso Bamboo Shoots

Advanced Science, EarlyView.
Organic mulching reprograms Moso bamboo shoot development, enhancing yield and nutritional quality. This multi‐omics study reveals that coordinated metabolic, transcriptional, and post‐transcriptional regulation drives stage‐specific quality formation, offering comprehensive insights into how this agricultural practice improves crop performance and ...
Bo Wang, Yanbin Wang, Chunyue Wang, Zishan Ahmad, Peixin Teng, Huijing Ni, Qiang Wei, Muthusamy Ramakrishnan   +7 more
wiley   +1 more source

The proteome and the metabolome [PDF]

Bioinformatics, 2003
Abstract High throughput technology is having an immense impact on biological research and one of the major challenges today is to use all this information to understand the complex network of interactions in the cell. Not only have we seen an exponential growth in genomic sequence data, but with the advent of transcriptome and proteome ...
openaire   +2 more sources

Leaf metabolome in arbuscular mycorrhizal symbiosis

, 2015
Schweiger R, Müller C. Leaf metabolome in arbuscular mycorrhizal symbiosis. Current Opinion in Plant Biology.
Schweiger, Rabea, Müller, Caroline
core   +1 more source

Lithium‐Doped Hydroxyapatite Nanowires Rejuvenate Senescent Macrophages Via the Lysosome‐Dependent Ferroptosis Axis to Promote Aged Bone Regeneration

Advanced Science, EarlyView.
Li‐nHAP+GelMA promotes mandibular bone regeneration in aged mice by remodeling the senescent immune microenvironment. Local delivery of Li‐nHAP restores lysosomal homeostasis in senescent macrophages, reduces intracellular labile Fe2+ accumulation, ROS production, and lipid peroxidation, thereby suppressing macrophage ferroptosis and senescence ...
Baixi Chen, Ziduan Ding, Ruomei Li, Cheng Zhu, Zhiyu Zhu, Zitong Yang, Luyao Qu, Jin Hao, Lunguo Xia, Bing Fang, Lu Liu   +10 more
wiley   +1 more source

Potential non-invasive biomarkers of chronic sleep disorders identified by salivary metabolomic profiling among middle-aged Japanese men

Scientific Reports
Sleep disorders have become a global social problem that increases the risk of developing mental illnesses and metabolic diseases. We aimed to identify biomarkers with which to non-invasively and objectively evaluate chronic sleep disorders.
Katsutaka Oishi, Yuta Yoshida, Kosuke Kaida, Kozue Terai, Hiroyuki Yamamoto, Atsushi Toyoda   +5 more
doaj   +1 more source

The Pathway Analysis Based on the Changed Metabolome.

, 2016
The Pathway Analysis Based on the Changed Metabolome.
Yang Wang (5921), Hong Lv (6493), Zhongkai Gu (3181425), Yan Shen (12156), Jing Li (10611), Zhe Wang (41178), Keke Huo (3181428)   +6 more
core   +1 more source