Results 101 to 110 of about 114,008 (316)

Enhanced Endophytic Colonization of Flavobacterium Promotes Plant Resistance to Fusarium Wilt

Advanced Science, EarlyView.
A natural microbial consortium employing a cross‐feeding strategy forms a stratified biofilm that promotes endophytic colonization of auxotrophic Flavobacterium. This enhanced colonization activates plant systemic resistance, effectively suppressing Fusarium wilt.
Xianfeng Ye, Changsheng Xu, Shuai Yao, Jiming Shen, Zeyuan Li, Yu Zhang, Fan Wu, Xinjie Li, Yanling Ji, Lei Zhang, Yan Huang, Zhoukun Li, Huayu Qin, Zhongli Cui   +13 more
wiley   +1 more source

Time resolved cell painting enables rapid assessment of cell phenotypes

SLAS Discovery
Cell Painting is an advanced imaging technique for drug discovery used to study cellular phenotypes by simultaneously labeling various organelles/structures and analyzing the resulting multidimensional phenotypic features through a sophisticated data ...
Franziska A. Hecker, Bruno Leggio, Tim Koenig, Karsten Niehaus, Sven Geibel   +4 more
doaj   +1 more source

Human metabolomics reveal daily variations under nutritional challenges specific to serum and skeletal muscle

Molecular Metabolism, 2018
Objective: Advances in the field of metabolomics and the concomitant development of bioinformatics tools constitute a promising avenue towards the development of precision medicine and personalized profiling for numerous disease states. Studies in animal
Shogo Sato, Evelyn B. Parr, Brooke L. Devlin, John A. Hawley, Paolo Sassone-Corsi   +4 more
doaj   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

The Changed Metabolome After Resveratrol Treatment.

, 2016
The Changed Metabolome After Resveratrol Treatment.
Yang Wang (5921), Hong Lv (6493), Zhongkai Gu (3181425), Yan Shen (12156), Jing Li (10611), Zhe Wang (41178), Keke Huo (3181428)   +6 more
core   +1 more source

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Taiwanofungus camphoratus-Derived Extracellular Vesicles as a Potential Cosmetic Bioactive Candidate for Protecting Keratinocytes from UVB-Induced Photoaging

Cosmetics
Ultraviolet B (UVB)-induced photoaging is characterized by oxidative stress, mitochondrial dysfunction, and epidermal barrier impairment. Although extracellular vesicles (EVs) have emerged as bioactive mediators of intercellular signaling, the ...
Han-Wen Hsieh, Mo-Rong Xu, Wen-Wei Hsiao, Sheng-Yang Wang   +3 more
doaj   +1 more source

Screening and optimization of indole-3-acetic acid production and phosphate solubilization by rhizobacterial strains isolated from Acacia cyanophylla root nodules and their effects on its plant growth

Journal of Genetic Engineering and Biotechnology, 2020
Background Plant growth-promoting rhizobacteria (PGPR) are known to improve plant growth and are used as biofertilizers, thanks to their numerous benefits to agriculture such as phosphorus solubilization and phytohormone production.
Sara Lebrazi, Karsten Niehaus, Hanna Bednarz, Mouhcine Fadil, Marwa Chraibi, Kawtar Fikri-Benbrahim   +5 more
doaj   +1 more source

Integration of the D‐Genome Reshapes Gene Transcription, Chromatin Architecture, and Metabolome of Allohexaploid Wheat, Leading to Enhanced Environmental Adaptability

Advanced Science, EarlyView.
Integration of the D‐genome reshapes gene transcription, chromatin architecture, and the metabolome of hexaploid wheat, leading to enhanced adaptability to salt, UV‐B, and alkali stress. ABSTRACT The hybridization‐led integration of the D‐genome into domesticated tetraploid wheat gave rise to allohexaploid wheat, the most cultivated wheat globally ...
Yanyan Liu, Tao Zhu, Ziru Zhou, Wei Chen, Chao He, Xinkai Zhou, Xin Wang, Chuanye Chen, Bo Yang, Jiaqi Wei, Caixia Lan, Mengmeng Liu, Handong Su, Qiang Li, Xin Hu, Siteng Bi, Weizhi Ouyang, Xingwang Li, Hailiang Mao, Masahiro Kishi, Kerstin Kaufmann, Alisdair R. Fernie, Dijun Chen, Wenhao Yan   +23 more
wiley   +1 more source

Chemical superclasses in the urine metabolome database.

, 2013
Chemical superclasses in the urine metabolome database.
Jenna Poelzer (453987), Ralf Bogumil (5492), Michael R. Wilson (363333), Cornelia Roehring (453991), Zerihun T. Dame (453986), Farid Aziat (453982), Faizath S. Yallou (453989), Jessica Huynh (453988), David S. Wishart (5821), Souhaila Bouatra (229871), Ramanarayan Krishnamurthy (229876), Rupasri Mandal (114829), Craig Knox (74884), Philip Liu (453985), Trent C. Bjorndahl (453983), An Chi Guo (74885), Fozia Saleem (453984), Nick Psychogios (453990), Edison Dong (229888)   +18 more
core   +1 more source