Results 81 to 90 of about 99,469 (217)

Techniques for Phenotyping the Gut Microbiota Metabolome

open access: yes, 2019
Omics strategies have triggered a revolution in the understanding of the microorganisms that reside in our body, and their implications in health and disease. For diagnosis and therapeutics, metabolomic fingerprinting is the most powerful approach, since
Marina Perez-Gordo   +9 more
core   +1 more source

Field-scale monitoring of green sea turtles (Chelonia mydas): Influence of site characteristics and capture technique on the blood metabolome

open access: yes, 2022
Given their threatened status, there is considerable interest in establishing monitoring techniques that can be used to evaluate the health of sea turtles in the wild.
Chaousis, S   +4 more
core   +1 more source

Diagnostic and Predictive Utility of Plasma Phosphoethanolamine Levels in Depressive Disorder: A Naturalistic Observational Study

open access: yesInternational Journal of Methods in Psychiatric Research
Objectives Plasma phosphoethanolamine (PEA) has been proposed as a potential biomarker for depressive disorder. To further assess its diagnostic utility and relevance across psychiatric conditions, we conducted a larger observational study in a ...
Noriyuki Kawamura   +6 more
doaj   +1 more source

Human metabolomics reveal daily variations under nutritional challenges specific to serum and skeletal muscle

open access: yesMolecular Metabolism, 2018
Objective: Advances in the field of metabolomics and the concomitant development of bioinformatics tools constitute a promising avenue towards the development of precision medicine and personalized profiling for numerous disease states. Studies in animal
Shogo Sato   +4 more
doaj   +1 more source

Thyroid Hormone Metabolites Quantified in Pup and Adult Rat Cerebellum, Cortex and Whole-Brain Samples Using an Automated Online SPE-LC-MS/MS Method

open access: yesMetabolites
Changes in thyroid hormone (TH) levels in rat brain at early developmental stages are correlated with adverse effects on offspring development. To characterize the ability of substances to interfere with the TH concentrations in, e.g., rat brain, it is ...
Christiane Hindrichs   +6 more
doaj   +1 more source

Metabolomics for Biomarker Discovery in Gastroenterological Cancer

open access: yesMetabolites, 2014
The study of the omics cascade, which involves comprehensive investigations based on genomics, transcriptomics, proteomics, metabolomics, etc., has developed rapidly and now plays an important role in life science research.
Shin Nishiumi   +5 more
doaj   +1 more source

Microbial Metabolomics [PDF]

open access: yesCurrent Genomics, 2011
Microbial metabolomics constitutes an integrated component of systems biology. By studying the complete set of metabolites within a microorganism and monitoring the global outcome of interactions between its development processes and the environment, metabolomics can potentially provide a more accurate snap shot of the actual physiological state of the
openaire   +2 more sources

Time resolved cell painting enables rapid assessment of cell phenotypes

open access: yesSLAS Discovery
Cell Painting is an advanced imaging technique for drug discovery used to study cellular phenotypes by simultaneously labeling various organelles/structures and analyzing the resulting multidimensional phenotypic features through a sophisticated data ...
Franziska A. Hecker   +4 more
doaj   +1 more source

Screening and optimization of indole-3-acetic acid production and phosphate solubilization by rhizobacterial strains isolated from Acacia cyanophylla root nodules and their effects on its plant growth

open access: yesJournal of Genetic Engineering and Biotechnology, 2020
Background Plant growth-promoting rhizobacteria (PGPR) are known to improve plant growth and are used as biofertilizers, thanks to their numerous benefits to agriculture such as phosphorus solubilization and phytohormone production.
Sara Lebrazi   +5 more
doaj   +1 more source

Characterization of the Wheat Leaf Metabolome during Grain Filling and under Varied N-Supply [PDF]

open access: yes, 2017
Progress in improving crop growth is an absolute goal despite the influence multifactorial components have on crop yield and quality. An Avalon × Cadenza doubled-haploid wheat mapping population was used to study the leaf metabolome of field grown wheat ...
Erban, A.   +22 more
core   +1 more source

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