Results 71 to 80 of about 99,693 (217)
Suppl Table 6 (serum metabolome).xlsx [PDF]
Serum metabolome composition.
Giulio Ferrero (6867179)
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Metabolomics to unveil and understand phenotypic diversity between pathogen populations [PDF]
Visceral leishmaniasis is caused by a parasite called Leishmania donovani, which every year infects about half a million people and claims several thousand lives. Existing treatments are now becoming less effective due to the emergence of drug resistance.
Breitling, Rainer, +58 more
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Principles of metabolome conservation in animals [PDF]
Metabolite levels shape cellular physiology and disease susceptibility, yet the general principles governing metabolome evolution are largely unknown. Here, we introduce a measure of conservation of individual metabolite levels among related species.
Orsolya Liska +13 more
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Metabolomics generates a profile of small molecules that are derived from cellular metabolism and can directly reflect the outcome of complex networks of biochemical reactions, thus providing insights into multiple aspects of cellular physiology. Technological advances have enabled rapid and increasingly expansive data acquisition with samples as small
Xiaojing Liu, Jason W. Locasale
openaire +2 more sources
HMDB: A knowledgebase for the human metabolome [PDF]
The Human Metabolome Database (HMDB, http:// www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics ...
Liu, P. +37 more
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Elemental metabolomics is quantification and characterization of total concentration of chemical elements in biological samples and monitoring of their changes. Recent advances in inductively coupled plasma mass spectrometry have enabled simultaneous measurement of concentrations of > 70 elements in biological samples.
Ping Zhang 0008 +2 more
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mzMatch-ISO: an R tool for the annotation and relative quantification of isotope-labelled mass spectrometry data [PDF]
<p>Motivation: Stable isotope-labelling experiments have recently gained increasing popularity in metabolomics studies, providing unique insights into the dynamics of metabolic fluxes, beyond the steady-state information gathered by routine mass ...
Achcar, Fiona, +23 more
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AbstractThe metabolome is the terminal downstream product of the genome and consists of the total complement of all the low‐molecular‐weight molecules (metabolites) in a cell, tissue, or organism. Metabolomics aims to measure a wide breadth of small molecules in the context of physiological stimuli or disease states.
Lee D, Roberts +3 more
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Overview plasma metabolome coverage. [PDF]
Overview plasma metabolome coverage.
Jessica Maltha (290877) +13 more
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AbstractBackgroundOncogenic transformation alters intracellular metabolism and contributes to the growth of malignant cells. Metabolomics, or the study of small molecules, can reveal insight about cancer progression that other biomarker studies cannot.
Gurparsad Singh Suri +3 more
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