Results 51 to 60 of about 114,008 (316)

Mass Spectrometry Data Repository Enhances Novel Metabolite Discoveries with Advances in Computational Metabolomics

open access: yesMetabolites, 2019
Mass spectrometry raw data repositories, including Metabolomics Workbench and MetaboLights, have contributed to increased transparency in metabolomics studies and the discovery of novel insights in biology by reanalysis with updated computational ...
Hiroshi Tsugawa   +5 more
doaj   +1 more source

Monophasic Variant of Salmonella Typhimurium Infection Affects the Serum Metabolome in Swine

open access: yesMicroorganisms, 2023
Salmonella is the most relevant foodborne zoonotic agent found in swine, and its presence in French herds is significant. Its carriage is asymptomatic, which makes it difficult to detect during rearing, thus increasing the risk of its presence on pork ...
Guillaume Larivière-Gauthier   +5 more
doaj   +1 more source

Taxonomic classification for microbiome analysis, which correlates well with the metabolite milieu of the gut

open access: yesBMC Microbiology, 2018
Background 16S rRNA gene amplicon sequencing analysis (16S amplicon sequencing) has provided considerable information regarding the ecology of the intestinal microbiome.
Yoshihisa Wakita   +5 more
doaj   +1 more source

Metabolomics in oncology

open access: yesCancer Reports, 2023
AbstractBackgroundOncogenic transformation alters intracellular metabolism and contributes to the growth of malignant cells. Metabolomics, or the study of small molecules, can reveal insight about cancer progression that other biomarker studies cannot.
Gurparsad Singh Suri   +3 more
openaire   +3 more sources

The human serum metabolome [PDF]

open access: yes, 2011
Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the metabolomics community to develop centralized ...
John W Newman   +76 more
core   +1 more source

Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research [PDF]

open access: yes, 2023
We read with interest the multiomic studies by Kong et al and Chen et al examining gut microbiome-metabolome interactions and potential diagnostic and classification biomarkers in colorectal cancer.1 2 Large-scale, multicentre, multisample, longitudinal ...
Jostins-Dean, Luke   +94 more
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

The Transcriptional Regulator Crt1 is Involved in The Pathogenic Lifestyle of Xanthomonas campestris pv. campestris B100

open access: yesPolish Journal of Microbiology
The γ-proteobacterium Xanthomonas campestris pv. campestris B100 is the causal agent of black rot disease in a wide range of economically important crops. In addition, X. campestris pv.
Korszańska Anna   +4 more
doaj   +1 more source

Microbiome and Metabolomics

open access: yesMedical Journal of Babylon, 2023
The relationship between microbiome and metabolomics by studying the microbiota living in the human body and studying their effects on the concentration of metabolites, also to study effects of microbiota colonization on other bacteria or living organism entering the body.
Noor S K Al-Khafaji   +10 more
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

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