Results 31 to 40 of about 99,693 (217)
Metabolites, 2019 Metabolomics is the systematic study of the small-molecule profiles of biological samples produced by specific cellular processes. The high-throughput technologies used in metabolomic investigations generate datasets where variables are strongly correlated and redundancy is present in the data.
Matteo Stocchero +5 more
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Microorganisms, 2023 An understanding of the changes in gut microbiome composition and its associated metabolic functions is important to assess the potential implications thereof on host health.
Aishwarya Murali +12 more
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Cancer Metabolomics and the Human Metabolome Database [PDF]
Metabolites, 2016 The application of metabolomics towards cancer research has led to a renewed appreciation of metabolism in cancer development and progression. It has also led to the discovery of metabolite cancer biomarkers and the identification of a number of novel cancer causing metabolites.
David S. Wishart +3 more
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Computational Metabolomics: A Framework for the Million Metabolome [PDF]
Chemical Research in Toxicology, 2016 "Sola dosis facit venenum." These words of Paracelsus, "the dose makes the poison", can lead to a cavalier attitude concerning potential toxicities of the vast array of low abundance environmental chemicals to which humans are exposed. Exposome research teaches that 80-85% of human disease is linked to environmental exposures.
Karan, Uppal +5 more
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Cardiovascular Metabolomics [PDF]
Circulation Research, 2018 Disturbances in cardiac metabolism underlie most cardiovascular diseases. Metabolomics, one of the newer omics technologies, has emerged as a powerful tool for defining changes in both global and cardiac-specific metabolism that occur across a spectrum of cardiovascular disease states.
Robert W, McGarrah +4 more
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anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data [PDF]
, 2008 Background: Compared to other omics techniques, quantitative metabolomics is still at its infancy. Complex sample preparation and analytical procedures render exact quantification extremely difficult. Furthermore, not only the actual measurement but also
Kümmel, Anne, +13 more
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Plants, 2013 Plants have developed sophisticated recognition systems for different kinds of pathogens. Pathogen-associated molecular patterns (PAMPs) can induce various defense mechanisms, e.g., the production of reactive oxygen species (ROS) as an early event. Plant
Kalina Mrozek +2 more
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Antibiotic-Induced Changes in Microbiome-Related Metabolites and Bile Acids in Rat Plasma
Metabolites, 2020 Various environmental factors can alter the gut microbiome’s composition and functionality, and modulate host health. In this study, the effects of oral and parenteral administration of two poorly bioavailable antibiotics (i.e., vancomycin and ...
Véronique de Bruijn +8 more
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Biomedicines, 2023 The minimum sample volume for capillary electrophoresis-Fourier transform mass spectrometry (CE-FTMS) useful for analyzing hydrophilic metabolites was investigated using samples obtained from colorectal cancer patients.
Tetsuo Sugishita +6 more
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Isorhamnetin Has Potential for the Treatment of Escherichia coli-Induced Sepsis
Molecules, 2019 Isorhamnetin is a flavonoid that is abundant in the fruit of Hippophae rhamnoides L. It is widely studied for its ability to modulate inflammatory responses. In this study, we evaluated the potential of isorhamnetin to prevent gram-negative sepsis.
Anil Kumar Chauhan +4 more
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