Results 11 to 20 of about 141,099 (288)

Metabolomics [PDF]

open access: yesCell Metabolism, 2007
Metabolomics is the systematic identification and quantitation of all metabolites in a given organism or biological sample. The enhanced resolution provided by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), along with powerful chemometric software, allows the simultaneous determination and comparison of thousands of chemical ...
Idle, Jeffrey R., Gonzalez, Frank J.
  +6 more sources

Cardiovascular Metabolomics [PDF]

open access: yesCirculation Research, 2018
Disturbances in cardiac metabolism underlie most cardiovascular diseases. Metabolomics, one of the newer omics technologies, has emerged as a powerful tool for defining changes in both global and cardiac-specific metabolism that occur across a spectrum of cardiovascular disease states.
Robert W, McGarrah   +4 more
openaire   +2 more sources

Aspergillus Metabolome Database for Mass Spectrometry Metabolomics [PDF]

open access: yesJournal of Fungi, 2021
The Aspergillus Metabolome Database is a free online resource to perform metabolite annotation in mass spectrometry studies devoted to the genus Aspergillus. The database was created by retrieving and curating information on 2811 compounds present in 601 different species and subspecies of the genus Aspergillus.
Alberto Gil-de-la-Fuente   +7 more
openaire   +3 more sources

Cell Metabolomics [PDF]

open access: yesOMICS: A Journal of Integrative Biology, 2013
Abstract Metabolomics technologies enable the examination and identification of endogenous biochemical reaction products, revealing information on the precise metabolic pathways and processes within a living cell. Metabolism is either directly or indirectly involved with every aspect of cell function, and metabolomics is thus believed
Aihua, Zhang   +4 more
openaire   +2 more sources

Elemental metabolomics [PDF]

open access: yesBriefings in Bioinformatics, 2017
Elemental metabolomics is quantification and characterization of total concentration of chemical elements in biological samples and monitoring of their changes. Recent advances in inductively coupled plasma mass spectrometry have enabled simultaneous measurement of concentrations of > 70 elements in biological samples.
Zhang, Ping   +2 more
openaire   +3 more sources

Targeted Metabolomics [PDF]

open access: yesCurrent Protocols in Molecular Biology, 2012
AbstractThe metabolome is the terminal downstream product of the genome and consists of the total complement of all the low‐molecular‐weight molecules (metabolites) in a cell, tissue, or organism. Metabolomics aims to measure a wide breadth of small molecules in the context of physiological stimuli or disease states.
Lee D, Roberts   +3 more
openaire   +2 more sources

Associations among Wine Grape Microbiome, Metabolome, and Fermentation Behavior Suggest Microbial Contribution to Regional Wine Characteristics. [PDF]

open access: yes, 2016
UnlabelledRegionally distinct wine characteristics (terroir) are an important aspect of wine production and consumer appreciation. Microbial activity is an integral part of wine production, and grape and wine microbiota present regionally defined ...
Allen, Greg   +6 more
core   +2 more sources

Methyl lucidone induces apoptosis and G2/M phase arrest via the PI3K/Akt/NF-κB pathway in ovarian cancer cells

open access: yesPharmaceutical Biology, 2020
Context Methyl lucidone (ML) from the dried fruit of Lindera erythrocarpa Makino (Lauraceae) exhibits cytotoxic effects in various cancer cell lines. However, its effects on ovarian cancer cells remain unknown.
Jae-Hwan Yoon   +7 more
doaj   +1 more source

Optimized Analytical Procedures for the Untargeted Metabolomic Profiling of Human Urine and Plasma by Combining Hydrophilic Interaction (HILIC) and Reverse-Phase Liquid Chromatography (RPLC)-Mass Spectrometry. [PDF]

open access: yes, 2015
Profiling of body fluids is crucial for monitoring and discovering metabolic markers of health and disease and for providing insights into human physiology.
Contrepois, Kévin   +2 more
core   +1 more source

Multi-omics integration accurately predicts cellular state in unexplored conditions for Escherichia coli. [PDF]

open access: yes, 2016
A significant obstacle in training predictive cell models is the lack of integrated data sources. We develop semi-supervised normalization pipelines and perform experimental characterization (growth, transcriptional, proteome) to create Ecomics, a ...
Kim, Minseung   +3 more
core   +2 more sources

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