Results 11 to 20 of about 99,469 (217)
Xenobiotic Metabolomics: Major Impact on the Metabolome [PDF]
Annual Review of Pharmacology and Toxicology, 2012 Xenobiotics are encountered by humans on a daily basis and include drugs, environmental pollutants, cosmetics, and even components of the diet. These chemicals undergo metabolism and detoxication to produce numerous metabolites, some of which have the potential to cause unintended effects such as toxicity.
Johnson, Caroline H +3 more
openaire +5 more sources
The human serum metabolome. [PDF]
PLoS ONE, 2011 Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the metabolomics community to develop centralized ...
Nikolaos Psychogios +23 more
doaj +2 more sources
Cell Metabolism, 2007 Metabolomics is the systematic identification and quantitation of all metabolites in a given organism or biological sample. The enhanced resolution provided by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), along with powerful chemometric software, allows the simultaneous determination and comparison of thousands of chemical ...
Idle, Jeffrey R., Gonzalez, Frank J.
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Metabolites, 2020 From an animal health perspective, relatively little is known about the typical or healthy ranges of concentrations for many metabolites in bovine biofluids and tissues. Here, we describe the results of a comprehensive, quantitative metabolomic characterization of six bovine biofluids and tissues, including serum, ruminal fluid, liver, Longissimus ...
Aidin Foroutan +8 more
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Metabolites, 2019 Metabolomics is the systematic study of the small-molecule profiles of biological samples produced by specific cellular processes. The high-throughput technologies used in metabolomic investigations generate datasets where variables are strongly correlated and redundancy is present in the data.
Matteo Stocchero +5 more
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Cancer Metabolomics and the Human Metabolome Database [PDF]
Metabolites, 2016 The application of metabolomics towards cancer research has led to a renewed appreciation of metabolism in cancer development and progression. It has also led to the discovery of metabolite cancer biomarkers and the identification of a number of novel cancer causing metabolites.
David S. Wishart +3 more
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Computational Metabolomics: A Framework for the Million Metabolome [PDF]
Chemical Research in Toxicology, 2016 "Sola dosis facit venenum." These words of Paracelsus, "the dose makes the poison", can lead to a cavalier attitude concerning potential toxicities of the vast array of low abundance environmental chemicals to which humans are exposed. Exposome research teaches that 80-85% of human disease is linked to environmental exposures.
Karan, Uppal +5 more
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The Earth Metabolome Initiative ... a brief presentation
, 2022 A brief presentation of the Earth Metabolome ...
The EMI Consortium
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Metabolome-defined obesity and the risk of future diabetes and mortality
, 2021 Supplementary data for "Metabolome-defined obesity and the risk of future diabetes and ...
Filip Ottosson (5473880)
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Metabolome-Defined Obesity and the Risk of Future Type 2 Diabetes and Mortality
, 2022 Objective Obesity is a key risk factor for type 2 diabetes, however, up to 20% of patients are normal weight. Our aim was to identify metabolite patterns reproducibly predictive of BMI, and subsequently to test if lean individuals who carry an obese ...
Olle Melander (25955) +9 more
core +1 more source