Results 231 to 240 of about 98,733 (348)

Single‐cell spatial transcriptomic sequencing and machine learning models uncover molecular mechanisms and diagnostic biomarkers of Peyronie's disease formation in rats

open access: yesVIEW, EarlyView.
Peyronie's disease (PD) is a common male reproductive system disorder. The exact etiology of PD remains unclear. This study aimed to investigate molecular and cellular changes in PD using single‐cell spatial transcriptomics. Abstract Peyronie's disease (PD), commonly known as penile induration, is a prevalent male reproductive system disorder with ...
Keyuan Lou   +6 more
wiley   +1 more source

I-SVVS: integrative stochastic variational variable selection to explore joint patterns of multi-omics microbiome data. [PDF]

open access: yesBrief Bioinform
Dang T   +13 more
europepmc   +1 more source

Aged Gut Microbiota Contributes to Cognitive Impairment and Hippocampal Synapse Loss in Mice

open access: yesAging Cell, EarlyView.
Li et al. revealed that aged gut microbiota induces cognitive decline and microglia‐mediated synapse loss. Fecal Bifidobacterium pseudolongum abundance was reduced in patients with cognitive impairment and microbiota transplantation from patients with fewer B.p abundance yielded worse cognitive behavior in mice.
Mingxiao Li   +12 more
wiley   +1 more source

Metabolomics: what's new? [PDF]

open access: yesFlavour and Fragrance Journal, 2010
Verpoorte, R., Choi, Y.H., Kim, H.K.
openaire   +3 more sources

Multi‐Omic Associations of Epigenetic Age Acceleration Are Heterogeneously Shaped by Genetic and Environmental Influences

open access: yesAging Cell, EarlyView.
The connections between epigenetic age acceleration (EAA) and the multi‐ome, as well as the extent to which these connections are driven by genetic and environmental factors, remain underexplored. We identified blood proteins, metabolites, and exposures associated with EAA in young adults and, using twin study designs, show that these associations are ...
Gabin Drouard   +5 more
wiley   +1 more source

Metabolome in progression to Alzheimer's disease [PDF]

open access: gold, 2011
Matej Orešič   +13 more
openalex   +1 more source

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