Results 171 to 180 of about 210,196 (287)

Evaluating Methods for High-Dimensional Mediation in Metabolomics Data. [PDF]

Environ Sci Technol
Hoffman SS, Liang D, Dunlop A, Everson T, Gaskins AJ, Jones DP, Hüls A, Marcus M, Naimi AI.   +8 more
europepmc   +1 more source

AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker

Advanced Science, EarlyView.
An AI‐enabled SERS platform integrates automated exosome enrichment with molecular fingerprinting to enable accurate early detection and differential diagnosis of ten common cancers. The system identifies exosomal dATP as a universal Raman biomarker, offering a scalable, noninvasive, and clinically translatable approach for precision oncology ...
Cai Zhang, Wen‐Hui Zhao, Duo Zuo, Tianxing Zhou, Wenjing Hou, Lingwei Wang, Shangheng Shi, Yang Yang, Yuanyuan Liu, Shao‐Kai Sun, Li Ren, Zhaoxiang Ye, Dingbin Liu, Dong Li, Xiaoyuan Chen, Jihui Hao   +15 more
wiley   +1 more source

Integrated transcriptomics and metabolomics revealed the role of the flavonoid pathway in the resistance of Zanthoxylum bungeanum against leaf rust

Xia Yang, Yun Wang, Yan Sun, Jiali Guo, Zhaojun Geng, Bingyao Wei, Peiqin Li, Guanghui Tang   +7 more
openalex   +1 more source

A cooperative learning framework for the integration of metabolomic data from multiple cohorts and common phenotype identification. [PDF]

Comput Struct Biotechnol J
Salanon E, Jules E, Comte B, Boccard J, Pujos-Guillot E.   +4 more
europepmc   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Metabolomic and lipidomic profiling of plasma in kidney stone patients: identification of potential biomarkers and therapeutic targets [PDF]

Ziyu Fang, Shenglan Gong, Ling Li, Shuwei Zhang, Wei He, Yuchen Gao, Yonghan Peng, Shu Meng, Yong Jia, Bangyu Zou, Shaoxiong Ming, Min Liu, Hao Dong, Chenghua Yang, Xu Gao, Xiaofeng Gao   +15 more
openalex   +1 more source

Additional file 3 of Comparative physiological and metabolomic analyses reveal that Fe3O4 and ZnO nanoparticles alleviate Cd toxicity in tobacco

, 2022
Congming Zou, Tianquan Lu, Ruting Wang, Peng Xu, Yifen Jing, Ruling Wang, Jin Xu, Jinpeng Wan   +7 more
openalex   +1 more source

Metabolomics-driven prediction of antibiotic resistance: a perspective on pre-genetic intervention. [PDF]

NPJ Antimicrob Resist
Hussein M, Creek DJ, Baker M, Rao GG, Li J, Velkov T.   +5 more
europepmc   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

MTHFR allele and one-carbon metabolic profile predict severity of COVID-19. [PDF]

Proc Natl Acad Sci U S A
Petrova B, Syphurs C, Culhane AJ, Chen J, Chen E, Cotsapas C, Esserman D, Montgomery RR, Kleinstein SH, Smolen KK, Mendez K, IMPACC Network, Lasky-Su J, Steen H, Levy O, Diray-Arce J, Kanarek N.   +16 more
europepmc   +1 more source