Results 171 to 180 of about 297,367 (349)

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

Advanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu, Yun Teng, Yinan Huang, Jingyao Mu, Lucy Teng, Hongjia Qian, Qiming Huang, Minmin Liu, Yi Zou, Lifeng Zhang, Michael L Merchant, Xiang Zhang, Jun Yan, Huang‐Ge Zhang   +13 more
wiley   +1 more source

Metabolomics: beyond biomarkers and towards mechanisms

Nature reviews. Molecular cell biology, 2016
C. Johnson, J. Ivanisevic, G. Siuzdak
semanticscholar   +1 more source

A roadmap for the XCMS family of software solutions in metabolomics

, 2015
Nathaniel G. Mahieu, Jessica Lloyd Genenbacher, Gary J. Patti   +2 more
openalex   +1 more source

Circadian and Sleep Metabolomics Across Species

, 2020
Dania Malik, Georgios K. Paschos, Amita Sehgal, Aalim M. Weljie   +3 more
openalex   +2 more sources

Identification and Annotation of Lipid Species in Metabolomics Studies Need Improvement [PDF]

, 2015
Gerhard Liebisch, Christer S. Ejsing, Kim Ekroos   +2 more
openalex   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

Advanced Science, EarlyView.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun, Miriayi Alimujiang, Wenfei Li, Shuqin Chen, Yingying Su, Tingting Hu, Xuhong Lu, Yafen Ye, Ningning Bai, Fan Hu, Xiaoya Li, Rongrong Xu, Jun Xu, Jiarui Zhao, Yan Lu, Xiaojing Ma, Ying Yang   +16 more
wiley   +1 more source

Targeted Metabolomics Analysis Reveals that Dietary Supranutritional Selenium Regulates Sugar and Acylcarnitine Metabolism Homeostasis in Pig Liver [PDF]

, 2019
Kai Zhang, Yunsheng Han, Qingyu Zhao, Tengfei Zhan, Ying Li, Wenjuan Sun, Shuang Li, Dandan Sun, Xueyang Si, Xiaonan Yu, Yuchang Qin, Chaohua Tang, Junmin Zhang   +12 more
openalex   +1 more source

FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine

Advanced Science, EarlyView.
This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang, Yinghui Xu, Xianpeng Wu, Mo Li, Changchen Xiao, Zaiyang Fu, Yongjian Chen, Qingju Li, Yating Ruan, Jing Zhao, Zhiwei Zhong, Jinghai Chen, Wei Zhu, Jinliang Nan, Cheng Ni, Xinyang Hu   +15 more
wiley   +1 more source

The critical role that spectral libraries play in capturing the metabolomics community knowledge

Metabolomics, 2022
Wout Bittremieux, Mingxun Wang, P. Dorrestein   +2 more
semanticscholar   +1 more source

Metabolomics and transcriptomics reveal defense mechanism of rice (Oryza sativa) grains under stress of 2,2′,4,4′-tetrabromodiphenyl ether

, 2019
Jie Chen, X. Chris Le, Lizhong Zhu
openalex   +1 more source