Results 211 to 220 of about 297,367 (349)

Analytical practices, use and needs of standard and reference materials in the German-speaking metabolomics community: results of an online survey. [PDF]

Metabolomics
Jaeger C, Lintelmann J, Franke R, Artati A, Cecil A, Broda F, Klawonn F, Erban A, Kopka J, Fuchs B, Sommer U, Neumann-Schaal M, O'Connor G, Standards and Reference Materials Working Group of the Deutsche Gesellschaft für Metabolomforschung (DGMet).   +13 more
europepmc   +1 more source

Metabolomics 2015 [PDF]

ELECTROPHORESIS, 2015
openaire   +2 more sources

Clinofibrate Disrupts the SNORA80B/YTHDC1‐Driven M6A Modification to Suppress Cholesterol Metabolism and Cisplatin Resistance in ESCC

Advanced Science, EarlyView.
This study uncovers a non‐canonical role of SNORA80B in ESCC, showing it mediates AR‐driven metabolic reprogramming via N⁶‐methyladenosine (m6A) methylation. By binding YTHDC1, SNORA80B stabilizes cholesterol‐metabolic enzyme mRNAs and promotes tumor progression. The FDA‐approved drug clinofibrate inhibits SNORA80B by disrupting cholesterol homeostasis,
Hongyu Yuan, Ge Ge, LiQiu Liu, Sijun Hu, Miaomiao Tian, Yongzhan Nie, Zitong Zhao, Yongmei Song   +7 more
wiley   +1 more source

Metabolomics and Pharmacometabolomics: Advancing Precision Medicine in Drug Discovery and Development. [PDF]

Metabolites
Stolaki EV, Psatha K, Aivaliotis M.
europepmc   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source

Differences in Flavour Compounds and Key Metabolic Markers in High-Quality Broiler Rooster Breast Muscle Based on Broad-Target Metabolomics and Volatile Metabolomics. [PDF]

Foods
Yang M, Liu X, Li R, Liang Z, Wang Q, Kong Y, Zhao Z, Wu Z, Kong L, Han W, Huang H.   +10 more
europepmc   +1 more source

Development of Age‐ and Sex‐Specific Metabolomics‐Based Biological Ageing Clocks for 10‐Year Mortality Prediction

Advanced Science, EarlyView.
Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng, Ruijie Xie, Bernd Holleczek, Hermann Brenner, Ben Schöttker   +4 more
wiley   +1 more source

Applications of metabolomics in cow health assessment. [PDF]

Metabolomics
Zhao X, Tsermoula P, Khakimov B.
europepmc   +1 more source

PLA2G16‐Mediated Tetracosatetraenoic Acid Rewires Fatty Acid Oxidation to Impair CD8+ T Cell Immune Function in Promoting Breast Cancer Lung Metastasis

Advanced Science, EarlyView.
Illustrating how tumor‐derived PLA2G16 regulates tetracosatetraenoic acid (C24:4 (n‐6)) accumulation and CD8+ T cell activation via the C24:4‐PPARα‐FAO axis in early metastatic niches, thereby promoting lung metastasis of triple‐negative breast cancer.
Yubi Gan, Die Meng, Lei Lang, Jing Luo, Peijin Dai, Chao Chang, Zexiu Lu, Yuetong Guo, Rui Wang, Shanchun Chen, Xi Tang, Yixuan Hou, Dongmei Tan, Manran Liu   +13 more
wiley   +1 more source

New Evidence in Male Infertility Diagnosis: The Role of Metabolomics. [PDF]

Cells
Peluso G, Serrao M, Urlandini L, Rago V, Aquila S, Vivacqua A.   +5 more
europepmc   +1 more source