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2016
Metabolomics is the quantitative analysis of a large number of low molecular weight metabolites that are intermediate or final products of all the metabolic pathways in a living organism. Any metabolic profiles detectable in a human biological fluid are caused by the interaction between gene expression and the environment.
NOTO, ANTONIO +2 more
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Metabolomics is the quantitative analysis of a large number of low molecular weight metabolites that are intermediate or final products of all the metabolic pathways in a living organism. Any metabolic profiles detectable in a human biological fluid are caused by the interaction between gene expression and the environment.
NOTO, ANTONIO +2 more
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2009
Metabolomics is essentially the study of all low molecular weight molecules in a biological system under defined conditions. In glycomics, there is much potential to gain insight into the biosynthesis of novel glycoconjugate structures by probing the metabolome for substrates that are suspected, or known, to be involved in the biosynthetic processes ...
Soo, Evelyn C., Hui, Joseph P. M.
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Metabolomics is essentially the study of all low molecular weight molecules in a biological system under defined conditions. In glycomics, there is much potential to gain insight into the biosynthesis of novel glycoconjugate structures by probing the metabolome for substrates that are suspected, or known, to be involved in the biosynthetic processes ...
Soo, Evelyn C., Hui, Joseph P. M.
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2019
The human metabolome is the cumulative product of ingested metabolites and those produced by the body and its microbiota. Together these metabolites can dynamically report on the health and disease state of an individual, as well as their response to drug treatments and other external perturbations.
David P, Marciano, Michael P, Snyder
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The human metabolome is the cumulative product of ingested metabolites and those produced by the body and its microbiota. Together these metabolites can dynamically report on the health and disease state of an individual, as well as their response to drug treatments and other external perturbations.
David P, Marciano, Michael P, Snyder
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Current Protocols in Molecular Biology, 2010
AbstractAlong with genes and proteins, metabolites play important roles in sustaining life. Their functions include “primary” functions in metabolism and energy storage, as well as “secondary” functions in cell‐to‐cell signaling, metal acquisition, and virulence. There remains much to be learned about the in vivo roles of metabolites.
Nawaporn, Vinayavekhin +1 more
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AbstractAlong with genes and proteins, metabolites play important roles in sustaining life. Their functions include “primary” functions in metabolism and energy storage, as well as “secondary” functions in cell‐to‐cell signaling, metal acquisition, and virulence. There remains much to be learned about the in vivo roles of metabolites.
Nawaporn, Vinayavekhin +1 more
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2014
Metabolites, the chemical entities that are transformed during metabolism, provide a functional readout of cellular biochemistry that offers the best prediction of the phenotype and the nature of a disease. Mass spectrometry now allows thousands of metabolites to be quantitated.
Francis G, Bowling, Mervyn, Thomas
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Metabolites, the chemical entities that are transformed during metabolism, provide a functional readout of cellular biochemistry that offers the best prediction of the phenotype and the nature of a disease. Mass spectrometry now allows thousands of metabolites to be quantitated.
Francis G, Bowling, Mervyn, Thomas
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2021
Metabolic reprogramming is an important characteristics of glioma, the most common form of malignant brain tumor. In this chapter, we aim to discuss some of the recently discovered metabolic alterations in glioma, including the dysregulated TCA cycle, amino acid, nucleotide, and lipid metabolism.
Sizhe, Feng, Yutong, Liu
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Metabolic reprogramming is an important characteristics of glioma, the most common form of malignant brain tumor. In this chapter, we aim to discuss some of the recently discovered metabolic alterations in glioma, including the dysregulated TCA cycle, amino acid, nucleotide, and lipid metabolism.
Sizhe, Feng, Yutong, Liu
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Clinica Chimica Acta, 2014
Characterization of metabolic changes is key to early detection, treatment, and understanding molecular mechanisms of diabetes. Diabetes represents one of the most important global health problems. Approximately 90% of diabetics have type 2 diabetes. Identification of effective screening markers is critical for early treatment and intervention that can
Ai-hua, Zhang +4 more
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Characterization of metabolic changes is key to early detection, treatment, and understanding molecular mechanisms of diabetes. Diabetes represents one of the most important global health problems. Approximately 90% of diabetics have type 2 diabetes. Identification of effective screening markers is critical for early treatment and intervention that can
Ai-hua, Zhang +4 more
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Evaluation of salivary metabolomics in oral leukoplakia and oral squamous cell carcinoma
Journal of Oral Pathology & Medicine, 2019BACKGROUND Metabolomics is the study of metabolome which describes the full repertoire of small molecules, and the analysis of salivary metabolomics may help in identifying tumor-specific biomarkers for early diagnosis and prediction of tumor progression.
G. Sridharan +3 more
semanticscholar +1 more source
OMICS: A Journal of Integrative Biology, 2012
Abstract Metabolome refers to the complete set of metabolites synthesized through a series of multiple enzymatic steps from various biochemical pathways processing the information encrypted in the plant genome. Knowledge about synthesis and regulation of various plant metabolic substances has improved substantially with availability ...
K D, Nadella +2 more
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Abstract Metabolome refers to the complete set of metabolites synthesized through a series of multiple enzymatic steps from various biochemical pathways processing the information encrypted in the plant genome. Knowledge about synthesis and regulation of various plant metabolic substances has improved substantially with availability ...
K D, Nadella +2 more
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Understanding the metabolome – challenges for metabolomics
Nutrition Bulletin, 2008SummaryMetabolomics is a comprehensive method for metabolite assessment, measuring the overall metabolic signature of biological samples. This approach opens up many possibilities in areas such as new biomarker discovery and hypothesis generation. The application of metabolomics is growing rapidly but many challenges must first be addressed before it ...
M. C. Walsh +3 more
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