Metabolomic analysis of human oral cancer cells with adenylate kinase 2 or phosphorylate glycerol kinase 1 inhibition. [PDF]
The purpose of this study was to use liquid chromatography-mass spectrometry (LC-MS) with XCMS for a quantitative metabolomic analysis of UM1 and UM2 oral cancer cells after knockdown of metabolic enzyme adenylate kinase 2 (AK2) or phosphorylate glycerol
Cheng, Siliangyu+6 more
core +1 more source
Metabolomics on the study of marine organisms
Marine ecosystems are hosts to a vast array of organisms, being among the most richly biodiverse locations on the planet. The study of these ecosystems is very important, as they are not only a significant source of food for the world but also have, in ...
L. Bayona, N. D. de Voogd, Y. Choi
semanticscholar +1 more source
Metabolomic analysis of cricket paralysis virus infection in Drosophila S2 cells reveals divergent effects on central carbon metabolism as compared with silkworm Bm5 cells [PDF]
High-throughput approaches have opened new opportunities for understanding biological processes such as persistent virus infections, which are widespread.
Meeus, Ivan+5 more
core +1 more source
Autophagy inducers can prevent cardiovascular aging and age-associated diseases including atherosclerosis. Therefore, we hypothesized that autophagy-inducing compounds that act on atherosclerosis-relevant cells might have a protective role in the ...
Giulia Cerrato+13 more
doaj +1 more source
MetaboAnalystR: an R package for flexible and reproducible analysis of metabolomics data
Summary: The MetaboAnalyst web application has been widely used for metabolomics data analysis and interpretation. Despite its user‐friendliness, the web interface has presented its inherent limitations (especially for advanced users) with regard to ...
Jasmine Chong, J. Xia
semanticscholar +1 more source
A Single Visualization Technique for Displaying Multiple Metabolite-Phenotype Associations. [PDF]
To assist with management and interpretation of human metabolomics data, which are rapidly increasing in quantity and complexity, we need better visualization tools.
Antonelli, Joseph+12 more
core +1 more source
Budding yeast has from the beginning been a major eukaryotic model for the study of metabolic network structure and function. This is attributable to both its genetic and biochemical capacities and its role as a workhorse in food production and biotechnology.
Amy A. Caudy+3 more
openaire +3 more sources
NMR Spectroscopy for Metabolomics Research
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the three principal analytical techniques used in metabolomics (the other two being gas chromatography coupled to mass spectrometry (GC-MS) and liquid chromatography ...
A. Emwas+10 more
semanticscholar +1 more source
The metabolomics of psoriatic disease. [PDF]
Metabolomics is an emerging new "omics" field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes ...
Afifi, Ladan+6 more
core
Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future [PDF]
Metabolomics and lipidomics are emerging methods for detailed phenotyping of small molecules in samples. It is hoped that such data will: (i) enhance baseline prediction of patient response to pharmacotherapies (beneficial or adverse); (ii) reveal ...
Preiss, David+3 more
core +2 more sources