Results 91 to 100 of about 89,220 (264)

From Neurotransmission to Retinal Pathophysiology: Unraveling the Role of GABA Receptors in Retinal Disease Progression

Journal of Neurochemistry, Volume 169, Issue 8, August 2025.
GABA receptors, widely expressed in the retina, play a key role in lateral inhibition and synaptic regulation. Emerging evidence links their dysregulation to retinal diseases such as diabetic retinopathy, retinitis pigmentosa, glaucoma, and age‐related macular degeneration.
Alan E. Medina Arellano, Jesus Silvestre Albert‐Garay, Nadia Flores Huerta, Karla Tovar Hernández, Matilde Ruiz‐Cruz, Lenin Ochoa‐de la Paz   +5 more
wiley   +1 more source

Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures.

, 1991
Jae‐Young Koh, Elizabeth E. Palmer, CW Cotman   +2 more
openalex   +1 more source

Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus [PDF]

, 1996
Domenico E. Pellegrini‐Giampietro, Serenella Albani Torregrossa, Flavio Moroni   +2 more
openalex   +1 more source

Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction

Proceedings of the National Academy of Sciences of the United States of America, 2015
Adam G. Walker, Cody J. Wenthur, Zixiu Xiang, J. M. Rook, K. Emmitte, C. Niswender, C. Lindsley, P. Conn   +7 more
semanticscholar   +1 more source

Non‐ionotropic NMDAR signalling activates Panx1 to induce P2X4R‐dependent long‐term depression in the hippocampus

The Journal of Physiology, Volume 603, Issue 15, Page 4367-4381, 1 August 2025.
Abstract figure legend Stimulation of the Shaffer collateral pathway at 3 Hz activates non‐ionotropic NMDA receptors. This subsequently leads to Src kinase mediated phosphorylation of pannexin‐1 (Panx1), which releases ATP from the postsynaptic cell. ATP acts as a ligand for P2X4 receptors to induce long‐term depression (LTD). Abstract In recent years,
Allison C. Nielsen, Connor L. Anderson, Carina Ens, Andrew K. J. Boyce, Roger J. Thompson   +4 more
wiley   +1 more source

Activation of a metabotropic glutamate receptor increases intracellular calcium concentrations in neurons of the avian cochlear nucleus [PDF]

, 1995
Lance Zirpel, E. A. Lachica, EW Rubel
openalex   +1 more source

Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator

Science, 2014
Huixian Wu, Chong Wang, K. Gregory, K. Gregory, G. Han, Hyekyung P. Cho, Yao Xia, C. Niswender, V. Katritch, J. Meiler, V. Cherezov, P. Conn, R. Stevens   +12 more
semanticscholar   +1 more source

Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity

The Journal of Physiology, Volume 603, Issue 15, Page 4237-4253, 1 August 2025.
Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez, Leigh E. Wicki‐Stordeur, Annika V. Ariano, Leigh Anne Swayne   +3 more
wiley   +1 more source

Metabotropic glutamate receptors in spatial and nonspatial learning in rats studied by means of agonist and antagonist application. [PDF]

, 1995
Gernot Riedel, Wolfram Wetzel, Klaus G. Reymann   +2 more
openalex   +1 more source

Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice

Journal of Physiology, 2015
K. Yasumatsu, Tomohiro Manabe, R. Yoshida, Ken Iwatsuki, H. Uneyama, I. Takahashi, Y. Ninomiya   +6 more
semanticscholar   +1 more source