Inhibiting metabotropic glutamate receptor 5 after stroke restores brain function and connectivity. [PDF]
Hakon J +13 more
europepmc +1 more source
Radiosynthesis and Evaluation of 11C-Labeled Isoindolone-Based Positive Allosteric Modulators for Positron Emission Tomography Imaging of Metabotropic Glutamate Receptor 2. [PDF]
Li Y +19 more
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Alpha-secretase inhibition impairs Group I metabotropic glutamate receptor-mediated protein synthesis, long-term potentiation and long-term depression. [PDF]
Mockett BG +4 more
europepmc +1 more source
Psychotic symptoms associated increased CpG methylation of metabotropic glutamate receptor 8 gene in Chinese Han males with schizophrenia and methamphetamine induced psychotic disorder: a longitudinal study. [PDF]
Dong H +5 more
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Activation of Metabotropic Glutamate Receptor 3 Modulates Thalamo-accumbal Transmission and Rescues Schizophrenia-Like Physiological and Behavioral Deficits. [PDF]
Dogra S +9 more
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The novel peptide LCGM-10 attenuates metabotropic glutamate receptor 5 activity and demonstrates behavioral effects in animal models. [PDF]
Malyshev AV +8 more
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Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic control in postmortem brains of schizophrenia subjects. [PDF]
DelaCuesta-Barrutia J +12 more
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Metabotropic glutamate receptors
Cell and Tissue Research, 2006Metabotropic glutamate receptors (mGlus) are a family of G-protein-coupled receptors activated by the neurotransmitter glutamate. Molecular cloning has revealed eight different subtypes (mGlu1-8) with distinct molecular and pharmacological properties. Multiplicity in this receptor family is further generated through alternative splicing. mGlus activate
Ferraguti F., Shigemoto R.
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