Role and Mechanism of Microglia in White Matter Injury Recovery in Ischemic Stroke
Immunity, Inflammation and Disease, Volume 13, Issue 8, August 2025.Many studies have shown that stroke can cause microglia activation, and activated microglia differentiate into different types according to different time and region, and different types of microglia play an important role in the process of white matter recovery.
Yi‐Sha Guo +3 more
wiley +1 more source
Metabotropic glutamate receptors mediate excitatory transmission in the nucleus of the solitary tract [PDF]
, 1992 SR Glaum, RJ Miller
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Journal of Medical Virology, Volume 97, Issue 8, August 2025.ABSTRACT Kaposi's sarcoma‐associated herpesvirus (KSHV) is a human double‐stranded DNA virus that is responsible for the development of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), multicentric Castleman's disease (MCD), and KSHV inflammatory cytokine syndrome (KICS).
Quanyuan Wan, Andrew J. Tucker, Jun Zhao
wiley +1 more source
Modulation of calcium currents by a metabotropic glutamate receptor involves fast and slow kinetic components in cultured hippocampal neurons [PDF]
, 1993 Yoshinori Sahara, GL Westbrook
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Astrocyte in Neurological Disease: Pathogenesis and Therapy
MedComm, Volume 6, Issue 8, August 2025.This review provides comprehensive overview of astrocytes in neurological disorders. Astrocytes contribute to neurological disorders via A1/A2 polarization, inducing neuroinflammation, synaptic, and BBB dysfunction. Metabolic disturbances in glucose, lipid, and amino acid pathways leading to oxidative stress and mitochondrial damage.
Meihui Huang +4 more
wiley +1 more source
Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: An in situ hybridization study in adult and developing rat [PDF]
, 1992 Ryuichi Shigemoto +2 more
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Molecular Mechanisms of Chronic Pain and Therapeutic Interventions
MedComm, Volume 6, Issue 8, August 2025.We offer a comprehensive overview of the distinctive molecular mechanisms underlying nociceptive, neuropathic, and nociplastic pain, including the immune responses, ion channels, monoaminergic imbalance, and neuroinflammation. Subsequently, we summarized the status quo of nociceptive, neuropathic, and nociplastic pain managementmanipulation.
Zhen Li +8 more
wiley +1 more source
Movement Disorders, Volume 40, Issue 8, Page 1561-1571, August 2025.Abstract Background Fatigue in Parkinson's disease (PD) is a prevalent and debilitating non‐motor symptom. Despite its significant impact on quality of life, the underlying neurochemical and network‐based mechanisms remain poorly understood. Objectives This observational study applied a multimodal imaging approach to explore potential links between the
Ilaria Antonella Di Vico +14 more
wiley +1 more source
PROTEOMICS, Volume 25, Issue 15, Page 42-49, August 2025.ABSTRACT One of the traditional treatments in Alzheimer's disease (AD) is administration of memantine, the NMDA receptor antagonist. However, the molecular mechanism of the complex memantine action and the impact on the hippocampal proteome in humans is unknown.
Ivo Fabrik +12 more
wiley +1 more source
The effects of (RS)‐α‐cyclopropyl‐4‐phosphonophenylglycine ((RS)‐CPPG), a potent and selective metabotropic glutamate receptor antagonist [PDF]
, 1996 Nick J. Toms +4 more
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