Results 161 to 170 of about 52,074 (275)

The Metabotropic Glutamate 2/3 Receptor Agonist LY379268 Blocked Nicotine-Induced Increases in Nucleus Accumbens Shell Dopamine only in the Presence of a Nicotine-Associated Context in Rats [PDF]

, 2011
Manoranjan S. D’Souza, Matthias E. Liechti, Ana M. Ramirez-Niño, Ronald Kuczenski, Athina Markou   +4 more
openalex   +1 more source

Optogluram-2: a subtype-selective photoswitchable positive allosteric modulator for metabotropic glutamate receptor 4 [PDF]

, 2023
Silvia Panarello, Aleix González-Díez, Alice E. Berizzi, Fanny Malhaire, Roser Borràs‐Tudurí, Xavier Rovira, Laurent Prézeau, Jean‐Philippe Pin, Cyril Goudet, Amadeu Llebaria, Xavier Gómez‐Santacana   +10 more
openalex   +1 more source

(2S,1’R, 2'R, 3'R)-2-(2,3-Dicarboxycyclopropyl)-glycine (DCG-IV): A type-specific agonist for metabotropic glutamate receptor negatively coupled with adenylate cyclase in rat hippocampus.

, 1994
Mutsumi Maruyama, Mariko Nakazawa
openalex   +1 more source

Functional coupling of the metabotropic glutamate receptor, InsP₃ receptor and L‐type Ca²⁺ channel in mouse CA1 pyramidal cells [PDF]

, 2012
Hiroyuki Kato, Hidetoshi Kassai, Ayako M. Watabe, Atsu Aiba, Toshiya Manabe   +4 more
openalex   +1 more source

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

British Journal of Pharmacology, Volume 182, Issue 14, Page 3178-3210, July 2025.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison, Clauda Abboud, Dayana Abboud, Abdulrasheed O. Abdulrahman, Ana‐Nicoleta Bondar, Julie Dam, Zafiroula Georgoussi, Jesús Giraldo, Anemari Horvat, Christos Karoussiotis, Alba Paz‐Castro, Miriam Scarpa, Hannes Schihada, Nicole Scholz, Bilge Güvenc Tuna, Nina Vardjan   +15 more
wiley   +1 more source

Operant self-stimulation of thalamic terminals in the dorsomedial striatum is constrained by metabotropic glutamate receptor 2. [PDF]

Neuropsychopharmacology, 2020
Johnson KA, Voyvodic L, Loewinger GC, Mateo Y, Lovinger DM.   +4 more
europepmc   +1 more source

Allosterism in the adenosine A2A and cannabinoid CB2 heteromer

British Journal of Pharmacology, Volume 182, Issue 14, Page 3371-3384, July 2025.
Abstract Background and Purpose Allosterism is a regulatory mechanism for GPCRs that can be attained by ligand‐binding or protein–protein interactions with another GPCR. We have studied the influence of the dimer interface on the allosteric properties of the A2A receptor and CB2 receptor heteromer.
Claudia Llinas del Torrent, Iu Raïch, Angel Gonzalez, Jaume Lillo, Nil Casajuana‐Martin, Rafael Franco, Leonardo Pardo, Gemma Navarro   +7 more
wiley   +1 more source

Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT2A·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function [PDF]

, 2012
José L. Moreno, Carolina Muguruza, Adrienne Umali, Steven Mortillo, Terrell Holloway, Fuencisla Pilar-Cuéllar, Giuseppe Mocci, Jeremy Seto, Luís F. Callado, Rachael L. Neve, Graeme Milligan, Stuart C. Sealfon, Juan F. López‐Giménez, J. Javier Meana, Deanna L. Benson, Javier González‐Maeso   +15 more
openalex   +1 more source

The path to the G protein‐coupled receptor structural landscape: Major milestones and future directions

British Journal of Pharmacology, Volume 182, Issue 14, Page 3225-3248, July 2025.
G protein‐coupled receptors (GPCRs) play a crucial role in cell function by transducing signals from the extracellular environment to the inside of the cell. They mediate the effects of various stimuli, including hormones, neurotransmitters, ions, photons, food tastants and odorants, and are renowned drug targets.
Małgorzata M. Kogut‐Günthel, Zeenat Zara, Alessandro Nicoli, Alexandra Steuer, Marta Lopez‐Balastegui, Jana Selent, Sanjai Karanth, Melanie Koehler, Antonella Ciancetta, Layara Akemi Abiko, Franz Hagn, Antonella Di Pizio   +11 more
wiley   +1 more source

N-Acetyl-Cysteine Causes Analgesia by Reinforcing the Endogenous Activation of Type-2 Metabotropic Glutamate Receptors [PDF]

, 2012
Matteo Bernabucci, Serena Notartomaso, Cristina Zappulla, Francesco Fazio, Milena Cannella, Marta Motolese, Giuseppe Battaglia, Valeria Bruno, Roberto Gradini, Ferdinando Nicoletti   +9 more
openalex   +1 more source