GABAB Receptors Mediate Intracellular Calcium Release in Astrocytes of the Prefrontal Cortex
We took advantage of GLAST‐promoter driven GCaMP6s expression in astrocytes to study Ca2+ signaling in astrocytes of the young adult prefrontal cortex in response to GABA with confocal Ca2+ imaging. The results show that GABA induces Ca2+ signaling via the stimulation of the metabotropic GABAB receptor in astrocytes.
Jennifer Bostel+2 more
wiley +1 more source
Age-dependent impairment of metabotropic glutamate receptor 2-dependent long-term depression in the mouse striatum by chronic ethanol exposure. [PDF]
Johnson KA+3 more
europepmc +1 more source
Estrogenic regulation of hippocampal inhibitory system across lifespan
Abstract Estrogens produced in peripheral tissues and locally in the brain are potent neuromodulators. The function of the hippocampus, a brain region essential for episodic memory and spatial navigation, relies on the activity of ensembles of excitatory neurons whose activity is temporally and spatially coordinated by a wide diversity of inhibitory ...
Pablo Méndez+2 more
wiley +1 more source
The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety [PDF]
Vasilios Grivas+2 more
openalex +1 more source
Paraneoplastic Cerebellar Ataxia and Antibodies to Metabotropic Glutamate Receptor 2 (2689) [PDF]
Raquel Ruiz‐García+6 more
openalex +1 more source
Chronic pain is associated with cognitive deficits. Palmitoylethanolamide (PEA) has been shown to ameliorate pain and pain-related cognitive impairments by restoring glutamatergic synapses functioning in the spared nerve injury (SNI) of the sciatic nerve
Serena Boccella+17 more
doaj
EHMTI-0158. Positive allosteric modulators (PAMS) of the metabotropic glutamate receptor 2 (MGLUR2) are effective against nerve injury induced facial allodynia in rats [PDF]
C Horváth+5 more
openalex +1 more source
[ carbonyl - 11 C]4-Fluoro- N -methyl- N -(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([ 11 C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain [PDF]
Jinsoo Hong+9 more
openalex +1 more source
Deletion of the type 2 metabotropic glutamate receptor increases heroin abuse vulnerability in transgenic rats [PDF]
J Gao+6 more
openalex +1 more source