Results 181 to 190 of about 52,982 (243)

Borneol's Pre-Clinical Analgesic Efficacy: Mediated by Receptor and Immune Mechanisms. [PDF]

J Pain Res
Zhou Y, Mei X, Wang C.
europepmc   +1 more source

Profiling the Impact of mGlu₇/Elfn1 Protein Interactions on the Pharmacology of mGlu₇ Allosteric Modulators. [PDF]

ACS Chem Neurosci
Lei X, Xiang Z, Rodriguez AL, Wilson ML, Niswender CM.   +4 more
europepmc   +1 more source

Acute Alcohol-Induced Changes Measured With Metabotropic Glutamate Receptor 5 Positron Emission Tomography. [PDF]

Addict Biol
Raval NR, Smart K, Angarita GA, Miller R, Huang Y, Krystal JH, Carson RE, Cosgrove KP, O'Malley SS, Hillmer AT.   +9 more
europepmc   +1 more source

Potentiation of group III metabotropic glutamate receptors positively affects neurophysiological features in a mouse model of Rett syndrome. [PDF]

J Pharmacol Exp Ther
Dong HW, Weiss K, Dickerson JW, Meadows MJ, Zagol-Ikapitte I, Boutaud O, Rook JM, Neul JL, Niswender CM.   +8 more
europepmc   +1 more source

Inhibition of metabotropic glutamate receptor-5 alleviates hepatic steatosis by enhancing autophagy <i>via</i> activation of the AMPK signaling pathway. [PDF]

World J Gastroenterol
Tao M, Zhang LL, Zhou GH, Wang C, Luo X.
europepmc   +1 more source

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Cholesterol Localization Around the Metabotropic Glutamate Receptor 2.

The Journal of Physical Chemistry B, 2020
The metabotropic glutamate receptor (mGluR) 2 plays a key role in the central nervous system. mGluR2 has been shown to be regulated by its surrounding lipid environment, especially by cholesterol, by an unknown mechanism.
M. Kurth, Fabio Lolicato, Angélica Sandoval-Pérez, Helman Amaya-Espinosa, Alexander Teslenko, I. Sinning, R. Beck, B. Brügger, Camilo Aponte-Santamaría   +8 more
semanticscholar   +4 more sources

Metabotropic Glutamate Receptor 2 Activators [PDF]

, 2014
Schizophrenia is a common and severe, often disabling psychiatric illness of unknown aetiology that affects approximately 24 million people worldwide. The illness is characterized by symptomatology comprising positive symptoms (hallucinations and delusional behaviours), negative symptoms (anhedonia, social withdrawal and apathy) and cognitive ...
J. Cid, A. Trabanco, H. Lavreysen
semanticscholar   +2 more sources

Specificity of metabotropic glutamate receptor 2 coupling to G proteins.

Molecular Pharmacology, 2003
Metabotropic glutamate receptor 2 (mGluR2) is a class 3 G protein-coupled receptor and an important mediator of synaptic activity in the central nervous system. Previous work demonstrated that mGluR2 couples to pertussis toxin (PTX)-sensitive G proteins. However, the specificity of mGluR2 coupling to individual members of the G(i/o) family is not known.
P. Kammermeier, Margaret I Davis, S. Ikeda   +2 more
semanticscholar   +4 more sources